Pineoblastoma is uniquely tolerant of mutually exclusive loss of DICER1, DROSHA or DGCR8

被引:17
作者
de Kock, Leanne [1 ]
Rivera, Barbara [2 ,4 ,5 ]
Foulkes, William D. [3 ,4 ,5 ,6 ]
机构
[1] Univ Western Australia, Med Res Ctr, QEII Med Ctr, Harry Perkins Inst Med Res, Perth, WA, Australia
[2] IDIBELL, Program Mol Mech & Expt Therapy Oncol Oncobell, Barcelona, Spain
[3] McGill Univ, Dept Human Genet, Montreal, PQ, Canada
[4] McGill Univ, Gerald Bronfman Dept Oncol, Montreal, PQ, Canada
[5] Jewish Gen Hosp, Segal Canc Ctr, Lady Davis Inst, Canc Axis, 3755 Cote St Catherine Rd, Montreal, PQ H3T 1E2, Canada
[6] McGill Univ, Ctr Hlth, Res Inst, Canc Res Program, Montreal, PQ, Canada
基金
加拿大健康研究院;
关键词
HETEROZYGOSITY; MUTATIONS;
D O I
10.1007/s00401-020-02139-5
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页码:1115 / 1118
页数:4
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