DIABETES Cardiovascular benefits of metformin in T1DM

被引:4
作者
Snell-Bergeon, Janet K. [1 ]
机构
[1] Univ Colorado, Barbara Davis Ctr Childhood Diabet, Barbara Davis Ctr, Anschutz Med Campus,POB F527, Aurora, CO 80045 USA
关键词
INSULIN-RESISTANCE; TYPE-1;
D O I
10.1038/nrendo.2017.116
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Results from the Reducing with Metformin Vascular Adverse Lesions (REMOVAL) study show for the first time that metformin has a cardiovascular benefit in patients with type 1 diabetes mellitus (T1DM), although the benefit was limited to tertiary outcomes and was modest. Additional measures are therefore needed to reduce cardiovascular disease in patients with T1DM.
引用
收藏
页码:565 / +
页数:2
相关论文
共 50 条
[21]   A Review of Insulin Resistance in Type 1 Diabetes: Is There a Place for Adjunctive Metformin? [J].
Gagan Priya ;
Sanjay Kalra .
Diabetes Therapy, 2018, 9 :349-361
[22]   INSULIN RESISTANCE AND IATROGENIC HYPERINSULINEMIA IN TYPE 1 DIABETES - NORM OR COMPLICATION? ROLE OF METFORMIN IN TYPE 1 DIABETES MELLITUS [J].
Bekier, Malgorzata ;
Szkutnik-Fiedler, Danuta ;
Uruska, Aleksandra .
ACTA POLONIAE PHARMACEUTICA, 2023, 80 (04) :531-539
[23]   Does obesity cause type 2 diabetes mellitus (T2DM)? Or is it the opposite? [J].
Malone, John I. ;
Hansen, Barbara C. .
PEDIATRIC DIABETES, 2019, 20 (01) :5-9
[24]   Cardiovascular Disease in Type 1 Diabetes Mellitus: Epidemiology and Management of Cardiovascular Risk [J].
Colom, Cristina ;
Rull, Anna ;
Sanchez-Quesada, Jose Luis ;
Perez, Antonio .
JOURNAL OF CLINICAL MEDICINE, 2021, 10 (08)
[25]   The effect of obesity and type 2 diabetes (T2DM) on human metabolite rhythms [J].
Isherwood, Cheryl ;
Johnston, Jonathan D. ;
Skene, Debra J. .
PROCEEDINGS OF THE NUTRITION SOCIETY, 2016, 75 (OCE1) :E30-E30
[26]   The predicted mechanisms and evidence of probiotics on type 2 diabetes mellitus (T2DM) [J].
Bajinka, Ousman ;
Sylvain Dovi, Kodzovi ;
Simbilyabo, Lucette ;
Conteh, Ishmail ;
Tan, Yurong .
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2024, 130 (04) :475-490
[27]   Effect of metformin on clinical and biochemical hyperandrogenism in adolescent girls with type 1 diabetes [J].
Hafez, Mona ;
Musa, Noha ;
Elbehairy, Shaimaa ;
Atty, Sahar Abdel ;
Elbarbary, Menna ;
Amin, Maha .
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, 2019, 32 (05) :461-470
[28]   Metformin and the heart: Update on mechanisms of cardiovascular protection with special reference to comorbid type 2 diabetes and heart failure [J].
Schernthaner, Guntram ;
Brand, Kerstin ;
Bailey, Clifford J. .
METABOLISM-CLINICAL AND EXPERIMENTAL, 2022, 130
[29]   The Cardiovascular Effects of Metformin: Further Reasons to Consider An Old Drug as a Cornerstone in the Therapy of Type 2 Diabetes Mellitus [J].
Anfossi, Giovanni ;
Russo, Isabella ;
Bonomo, Katia ;
Trovati, Mariella .
CURRENT VASCULAR PHARMACOLOGY, 2010, 8 (03) :327-337
[30]   Risk Factors for Cardiovascular Disease in Type 1 Diabetes [J].
Nathan, David M. ;
Bebu, Ionut ;
Braffett, Barbara H. ;
Lachin, John M. ;
Orchard, Trevor J. ;
Cowie, Catherine C. ;
Lopes-Virella, Maria ;
Schutta, Mark .
DIABETES, 2016, 65 (05) :1370-1379