DIABETES Cardiovascular benefits of metformin in T1DM

被引：4
作者：
Snell-Bergeon, Janet K. [1 ]
机构：
[1] Univ Colorado, Barbara Davis Ctr Childhood Diabet, Barbara Davis Ctr, Anschutz Med Campus,POB F527, Aurora, CO 80045 USA
来源：
NATURE REVIEWS ENDOCRINOLOGY | 2017年 / 13卷 / 10期
关键词：
INSULIN-RESISTANCE; TYPE-1;
D O I：
10.1038/nrendo.2017.116
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Results from the Reducing with Metformin Vascular Adverse Lesions (REMOVAL) study show for the first time that metformin has a cardiovascular benefit in patients with type 1 diabetes mellitus (T1DM), although the benefit was limited to tertiary outcomes and was modest. Additional measures are therefore needed to reduce cardiovascular disease in patients with T1DM.
引用
收藏
页码：565 / +
页数：2
相关论文
共 50 条
  • [21] INSULIN RESISTANCE AND IATROGENIC HYPERINSULINEMIA IN TYPE 1 DIABETES - NORM OR COMPLICATION? ROLE OF METFORMIN IN TYPE 1 DIABETES MELLITUS
    Bekier, Malgorzata
    Szkutnik-Fiedler, Danuta
    Uruska, Aleksandra
    ACTA POLONIAE PHARMACEUTICA, 2023, 80 (04): : 531 - 539
  • [22] Does obesity cause type 2 diabetes mellitus (T2DM)? Or is it the opposite?
    Malone, John I.
    Hansen, Barbara C.
    PEDIATRIC DIABETES, 2019, 20 (01) : 5 - 9
  • [23] Cardiovascular Disease in Type 1 Diabetes Mellitus: Epidemiology and Management of Cardiovascular Risk
    Colom, Cristina
    Rull, Anna
    Sanchez-Quesada, Jose Luis
    Perez, Antonio
    JOURNAL OF CLINICAL MEDICINE, 2021, 10 (08)
  • [24] The effect of obesity and type 2 diabetes (T2DM) on human metabolite rhythms
    Isherwood, Cheryl
    Johnston, Jonathan D.
    Skene, Debra J.
    PROCEEDINGS OF THE NUTRITION SOCIETY, 2016, 75 (OCE1) : E30 - E30
  • [25] The predicted mechanisms and evidence of probiotics on type 2 diabetes mellitus (T2DM)
    Bajinka, Ousman
    Sylvain Dovi, Kodzovi
    Simbilyabo, Lucette
    Conteh, Ishmail
    Tan, Yurong
    ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, 2024, 130 (04) : 475 - 490
  • [26] Effect of metformin on clinical and biochemical hyperandrogenism in adolescent girls with type 1 diabetes
    Hafez, Mona
    Musa, Noha
    Elbehairy, Shaimaa
    Atty, Sahar Abdel
    Elbarbary, Menna
    Amin, Maha
    JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, 2019, 32 (05) : 461 - 470
  • [27] Metformin and the heart: Update on mechanisms of cardiovascular protection with special reference to comorbid type 2 diabetes and heart failure
    Schernthaner, Guntram
    Brand, Kerstin
    Bailey, Clifford J.
    METABOLISM-CLINICAL AND EXPERIMENTAL, 2022, 130
  • [28] The Cardiovascular Effects of Metformin: Further Reasons to Consider An Old Drug as a Cornerstone in the Therapy of Type 2 Diabetes Mellitus
    Anfossi, Giovanni
    Russo, Isabella
    Bonomo, Katia
    Trovati, Mariella
    CURRENT VASCULAR PHARMACOLOGY, 2010, 8 (03) : 327 - 337
  • [29] Risk Factors for Cardiovascular Disease in Type 1 Diabetes
    Nathan, David M.
    Bebu, Ionut
    Braffett, Barbara H.
    Lachin, John M.
    Orchard, Trevor J.
    Cowie, Catherine C.
    Lopes-Virella, Maria
    Schutta, Mark
    DIABETES, 2016, 65 (05) : 1370 - 1379
  • [30] Cardiovascular Function/Dysfunction in Adolescents with Type 1 Diabetes
    Nadeau, Kristen J.
    Reusch, Jane E. B.
    CURRENT DIABETES REPORTS, 2011, 11 (03) : 185 - 192
12345