Trends, patterns and psychological influences on COVID-19 vaccination intention: Findings from a large prospective community cohort study in England and Wales (Virus Watch)

被引:11
作者
Byrne, Thomas [1 ]
Patel, Parth [1 ]
Shrotri, Madhumita [1 ]
Beale, Sarah [1 ,2 ]
Michie, Susan [3 ]
Butt, Jabeer [4 ]
Hawkins, Nicky
Hardelid, Pia [5 ]
Rodger, Alison [6 ,7 ]
Aryee, Anna [1 ]
Braithwaite, Isobel [1 ]
Fong, Wing Lam Erica [1 ]
Fragaszy, Ellen [1 ,8 ]
Geismar, Cyril [1 ,2 ]
Kovar, Jana [2 ]
Navaratnam, Annalan M. D. [1 ,2 ]
Nguyen, Vincent [1 ,2 ]
Hayward, Andrew [2 ]
Aldridge, Robert W. [1 ]
Wijlaar, Linda [5 ]
Nastouli, Eleni [5 ,9 ]
Spyer, Moira [5 ,9 ]
Killingley, Ben [10 ,11 ]
Cox, Ingemar [12 ]
Lampos, Vasileios [12 ]
McKendry, Rachel A. [13 ,14 ]
Cheng, Tao [15 ]
Liu, Yunzhe [15 ]
Johnson, Anne M. [6 ]
Gibbs, Jo [6 ]
Gilson, Richard [6 ]
机构
[1] UCL, Inst Hlth Informat, Ctr Publ Hlth Data Sci, 222 Euston Rd, London NW1 2DA, England
[2] UCL, Inst Epidemiol & Hlth Care, 1-19 Torrington Pl, London WC1E 7HB, England
[3] UCL, Ctr Behav Change, 1-19 Torrington Pl, London WC1E 7HB, England
[4] Race Equal Fdn, 27 Greenwood Pl, London NW5 1LB, England
[5] UCL Great Ormond St Inst Child Hlth, Dept Populat Policy & Practice, 30 Guilford St, London WC1N 1EH, England
[6] UCL, Inst Global Hlth, 30 Guilford St, London WC1N 1EH, England
[7] Royal Free London NHS Fdn Trust, Pond St, London NW3 2QG, England
[8] London Sch Hyg & Trop Med, Dept Infect Dis Epidemiol, Keppel St, London WC1E 7HT, England
[9] Francis Crick Inst, 1 Midland Rd, London NW1 1AT, England
[10] Univ Nottingham, Sch Med, Div Epidemiol & Publ Hlth, Hlth Protect & Influenza Res Grp, Nottingham, England
[11] Univ Coll London Hosp, Euston Rd, London WC1H 8NJ, England
[12] UCL, Dept Comp Sci, 17-19 Gordon St, London WC1H 0AH, England
[13] UCL, London Ctr Nanotechnol, London, England
[14] UCL, Div Med, London, England
[15] UCL, Dept Civil Environm & Geomat Engn, SpaceTimeLab, London, England
基金
英国惠康基金; 英国工程与自然科学研究理事会;
关键词
COVID-19; Vaccine; Intention; Public Health; MINORITY ETHNIC-GROUPS; UNDER-REPRESENTATION;
D O I
10.1016/j.vaccine.2021.09.066
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background: Vaccination intention is key to the success of any vaccination programme, alongside vaccine availability and access. Public intention to take a COVID-19 vaccine is high in England and Wales compared to other countries, but vaccination rate disparities between ethnic, social and age groups has led to concern. Methods: Online survey of prospective household community cohort study participants across England and Wales (Virus Watch). Vaccination intention was measured by individual participant responses to 'Would you accept a COVID-19 vaccine if offered?', collected in December 2020 and February 2021. Responses to a 13-item questionnaire collected in January 2021 were analysed using factor analysis to investigate psychological influences on vaccination intention. Results: Survey response rate was 56% (20,785/36,998) in December 2020 and 53% (20,590/38,727) in February 2021, with 14,880 adults reporting across both time points. In December 2020, 1,469 (10%) participants responded 'No' or 'Unsure'. Of these people, 1,266 (86%) changed their mind and responded 'Yes' or 'Already had a COVID-19 vaccine' by February 2021. Vaccination intention increased across all ethnic groups and levels of social deprivation. Age was most strongly associated with vaccination intention, with 16-24-year-olds more likely to respond "Unsure" or "No" versus "Yes" than 65-74-year-olds in December 2020 (OR: 4.63, 95 %CI: 3.42, 6.27 & OR 7.17 95 %CI: 4.26,12.07 respectively) and February 2021 (OR: 27.92 95 %CI: 13.79, 56.51 & OR 17.16 95 %CI: 4.12, 71.55). The association between ethnicity and vaccination intention weakened, but did not disappear, over time. Both vaccine-and illness-related psychological fac-tors were shown to influence vaccination intention. Conclusions: Four in five adults (86%) who were reluctant or intending to refuse a COVID-19 vaccine in December 2020 had changed their mind in February 2021 and planned to accept, or had already accepted, a vaccine. (c) 2021 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
引用
收藏
页码:7108 / 7116
页数:9
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