Trends, patterns and psychological influences on COVID-19 vaccination intention: Findings from a large prospective community cohort study in England and Wales (Virus Watch)

被引：13

作者：

Byrne, Thomas ^{[1
]}

Patel, Parth ^{[1
]}

Shrotri, Madhumita ^{[1
]}

Beale, Sarah ^{[1
,2
]}

Michie, Susan ^{[3
]}

Butt, Jabeer ^{[4
]}

Hawkins, Nicky

Hardelid, Pia ^{[5
]}

Rodger, Alison ^{[6
,7
]}

Aryee, Anna ^{[1
]}

Braithwaite, Isobel ^{[1
]}

Fong, Wing Lam Erica ^{[1
]}

Fragaszy, Ellen ^{[1
,8
]}

Geismar, Cyril ^{[1
,2
]}

Kovar, Jana ^{[2
]}

Navaratnam, Annalan M. D. ^{[1
,2
]}

Nguyen, Vincent ^{[1
,2
]}

Hayward, Andrew ^{[2
]}

Aldridge, Robert W. ^{[1
]}

Wijlaar, Linda ^{[5
]}

Nastouli, Eleni ^{[5
,9
]}

Spyer, Moira ^{[5
,9
]}

Killingley, Ben ^{[10
,11
]}

Cox, Ingemar ^{[12
]}

Lampos, Vasileios ^{[12
]}

McKendry, Rachel A. ^{[13
,14
]}

Cheng, Tao ^{[15
]}

Liu, Yunzhe ^{[15
]}

Johnson, Anne M. ^{[6
]}

Gibbs, Jo ^{[6
]}

Gilson, Richard ^{[6
]}

机构：

[1] UCL, Inst Hlth Informat, Ctr Publ Hlth Data Sci, 222 Euston Rd, London NW1 2DA, England

[2] UCL, Inst Epidemiol & Hlth Care, 1-19 Torrington Pl, London WC1E 7HB, England

[3] UCL, Ctr Behav Change, 1-19 Torrington Pl, London WC1E 7HB, England

[4] Race Equal Fdn, 27 Greenwood Pl, London NW5 1LB, England

[5] UCL Great Ormond St Inst Child Hlth, Dept Populat Policy & Practice, 30 Guilford St, London WC1N 1EH, England

[6] UCL, Inst Global Hlth, 30 Guilford St, London WC1N 1EH, England

[7] Royal Free London NHS Fdn Trust, Pond St, London NW3 2QG, England

[8] London Sch Hyg & Trop Med, Dept Infect Dis Epidemiol, Keppel St, London WC1E 7HT, England

[9] Francis Crick Inst, 1 Midland Rd, London NW1 1AT, England

[10] Univ Nottingham, Sch Med, Div Epidemiol & Publ Hlth, Hlth Protect & Influenza Res Grp, Nottingham, England

[11] Univ Coll London Hosp, Euston Rd, London WC1H 8NJ, England

[12] UCL, Dept Comp Sci, 17-19 Gordon St, London WC1H 0AH, England

[13] UCL, London Ctr Nanotechnol, London, England

[14] UCL, Div Med, London, England

[15] UCL, Dept Civil Environm & Geomat Engn, SpaceTimeLab, London, England

来源：

VACCINE | 2021年 / 39卷 / 48期

基金：

英国惠康基金; 英国工程与自然科学研究理事会;

关键词：

COVID-19; Vaccine; Intention; Public Health; MINORITY ETHNIC-GROUPS; UNDER-REPRESENTATION;

D O I：

10.1016/j.vaccine.2021.09.066

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Background: Vaccination intention is key to the success of any vaccination programme, alongside vaccine availability and access. Public intention to take a COVID-19 vaccine is high in England and Wales compared to other countries, but vaccination rate disparities between ethnic, social and age groups has led to concern. Methods: Online survey of prospective household community cohort study participants across England and Wales (Virus Watch). Vaccination intention was measured by individual participant responses to 'Would you accept a COVID-19 vaccine if offered?', collected in December 2020 and February 2021. Responses to a 13-item questionnaire collected in January 2021 were analysed using factor analysis to investigate psychological influences on vaccination intention. Results: Survey response rate was 56% (20,785/36,998) in December 2020 and 53% (20,590/38,727) in February 2021, with 14,880 adults reporting across both time points. In December 2020, 1,469 (10%) participants responded 'No' or 'Unsure'. Of these people, 1,266 (86%) changed their mind and responded 'Yes' or 'Already had a COVID-19 vaccine' by February 2021. Vaccination intention increased across all ethnic groups and levels of social deprivation. Age was most strongly associated with vaccination intention, with 16-24-year-olds more likely to respond "Unsure" or "No" versus "Yes" than 65-74-year-olds in December 2020 (OR: 4.63, 95 %CI: 3.42, 6.27 & OR 7.17 95 %CI: 4.26,12.07 respectively) and February 2021 (OR: 27.92 95 %CI: 13.79, 56.51 & OR 17.16 95 %CI: 4.12, 71.55). The association between ethnicity and vaccination intention weakened, but did not disappear, over time. Both vaccine-and illness-related psychological fac-tors were shown to influence vaccination intention. Conclusions: Four in five adults (86%) who were reluctant or intending to refuse a COVID-19 vaccine in December 2020 had changed their mind in February 2021 and planned to accept, or had already accepted, a vaccine. (c) 2021 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

引用

页码：7108 / 7116

页数：9

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