Aza-annulation of polarized N,S- and N,N-ketene acetals with itaconic anhydride: Synthesis of novel functionalized 1,2,3,4-tetrahydro-2-pyridones and related azabicycles

被引：51

作者：

Chakrabarti, S

Panda, K

Misra, NC

Ila, H ^{[1
]}

Junjappa, H

机构：

[1] Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India

[2] BioOrgan Appl Mat Pvt Ltd, Bangalore 560058, Karnataka, India

来源：

SYNLETT | 2005年 / 09期

关键词：

alkaloids; annulation; esters; heterocycles; lactams; Michael addition; nitriles;

D O I：

10.1055/s-2005-868491

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of novel highly functionalized 2-oxo-(1,2,3,4-tetrahydropyridin-3-yl) acetic acids has been described via aza-annulation of both acyclic and cyclic alpha-oxo- and alpha-nitro-N,S-and-N,N-ketene acetals with itaconic anhydride.

引用

页码：1437 / 1441

页数：5

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