Advances in topiramate as prophylactic treatment for migraine

被引:12
作者
Hu, Chuan [1 ]
Zhang, Yixin [1 ]
Tan, Ge [1 ]
机构
[1] Chongqing Med Univ, Affiliated Hosp 1, Dept Neurol, Chongqing 400016, Peoples R China
关键词
migraine; prophylactic treatment; topiramate; DOUBLE-BLIND; PREVENTION; PLACEBO; SAFETY; PHARMACOLOGY; PREVALENCE; GUIDELINE; EFFICACY; CURRENTS; NEURONS;
D O I
10.1002/brb3.2290
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
It is well-known that topiramate as a kind of antiepileptic drug has been proved effective for migraine prevention in North America and Europe. However, topiramate is still viewed as an off-label medication for migraine treatment in China, partly because of the limited evidence in Chinese patients. We summarize the effects of topiramate on the frequency, severity, quality-of-life, and adverse event among migraine patients, including children and adolescent in this review, so as to provide reference for Chinese doctors.
引用
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页数:9
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