Synthesis of Indenopyridine Derivatives via MgI2-Promoted [2+4] Cycloaddition Reaction of In-situ Generated 2-Styrylmalonate from Donor-Acceptor Cyclopropanes and Chalconimines

被引：31

作者：

Verma, Kamal ^{[1
]}

Banerjee, Prabal ^{[1
]}

机构：

[1] Indian Inst Technol Ropar, Dept Chem, Nangal Rd, Rupnagar 140001, Punjab, India

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2018年 / 360卷 / 19期

关键词：

2-styrylmalonate; donor-acceptor cyclopropanes; indenopyridine; chalconimines; DIELS-ALDER REACTIONS; POTENTIAL ANTIDEPRESSANTS; MJ-III-65; NSC-706744; 4+2 ANNULATION; ROUTE; COMPLEXES; ANALOGS;

D O I：

10.1002/adsc.201800598

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An unexpected MgI2-promoted [2 + 4] cycloaddition reaction of in-situ generated 2-styrylmalonate from donor-acceptor cyclopropanes with chalconimines to synthesize highly substituted indenopyridine derivatives under the mild reaction conditions have been developed. Additionally, these derivatives were utilized for the synthesis of highly substituted 9-membered lactam by oxidative C=C bond cleavage and spiro [oxoindane-pyrrolidine] derivative via Meinwald type rearrangement.

引用

页码：3687 / 3692

页数：6

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