Critical evaluation of peripheral smear in cases of anemia with high mean corpuscular hemoglobin concentration in children: A series of four cases

被引：4

作者：

Sharma, Sunita ^{[1
]}

Pujani, Meenu ^{[1
]}

Pahuja, Sangeeta ^{[1
]}

Chandra, Jagdish ^{[2
]}

Rath, B. ^{[2
]}

Labhchand ^{[2
]}

机构：

[1] Lady Hardinge Med Coll & Associated Hosp, Dept Pathol, New Delhi 110001, India

[2] Lady Hardinge Med Coll & Associated Hosp, Dept Pediat, New Delhi 110001, India

来源：

INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY | 2010年 / 53卷 / 04期

关键词：

Anemia; mean corpuscular hemoglobin concentration; peripheral smear;

D O I：

10.4103/0377-4929.72094

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Mean corpuscular hemoglobin concentration (MCHC), a parameter that is reported as a part of a standard complete blood count by automated analyzer, is a measure of the concentration of hemoglobin in a given volume of packed red blood cell. Values of MCHC significantly above reference range are not physiologically possible due to limitations on solubility of hemoglobin. The high MCHC can give us a clue to certain type of hemolytic anemia and necessitate critical evaluation of peripheral smear to reach a definitive diagnosis. Here we are presenting a series of four cases with raised MCHC, emphasizing the importance of systematic and meticulous examination of the peripheral smear to render a definitive diagnosis.

引用

页码：820 / 823

页数：4