One-pot synthesis of iminoimidazolines under microwave irradiation in solvent-free conditions

被引：6

作者：

Servi, Sueleyman ^{[1
]}

Genc, Murat ^{[1
]}

机构：

[1] Firat Univ, Dept Chem, Fac Sci & Arts, TR-23169 Elazig, Turkey

来源：

SYNTHETIC COMMUNICATIONS | 2007年 / 37卷 / 18期

关键词：

imidazolidine-2-thione; iminoimidazoline; microwave irradiation; one-pot synthesis;

D O I：

10.1080/00397910701545320

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Substituted iminoimidazolines were synthesized from a one-pot reaction of aromatic or hetero-aromatic amines with imidazolidine-2-thione under solvent-free conditions using microwave irradiation with good to excellent yields.

引用

页码：3173 / 3179

页数：7

共 18 条

[1] MICROWAVE-ASSISTED ORGANIC-REACTIONS [J].

CADDICK, S .

TETRAHEDRON, 1995, 51 (38) :10403-10432

[2] HETEROAROMATIC ANALOGS OF THE ALPHA-2-ADRENORECEPTOR PARTIAL AGONIST CLONIDINE [J].

CHAPLEO, CB ;

BUTLER, RCM ;

ENGLAND, DC ;

MYERS, PL ;

ROACH, AG ;

SMITH, CFC ;

STILLINGS, MR ;

TULLOCH, IF .

JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (07) :1627-1630

[3]

CUPPS TL, Patent No. 6486190

[4]

CUPPS TL, Patent No. 5478858

[5] New aromatic iminoimidazolidine derivatives as α1-adrenoceptor antagonists:: A novel synthetic approach and pharmacological activity [J].

Dardonville, C ;

Goya, P ;

Rozas, I ;

Alsasua, A ;

Martín, MI ;

Borrego, MJ .

BIOORGANIC & MEDICINAL CHEMISTRY, 2000, 8 (07) :1567-1577

[6] DIHETEROCYCLIC COMPOUNDS FROM DITHIOCARBAMATES AND DERIVATIVES THEREOF .3. 3,3'-ARYLENEBIS(2,4-DIOXO-1,2,3,4-TETRAHYDROQUINAZOLINES) [J].

GARIN, J ;

MELENDEZ, E ;

MERCHAN, FL ;

MERINO, P ;

ORDUNA, J ;

TEJERO, T .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1990, 27 (05) :1341-1344

[7] Microwave-assisted from synthesis of 2-arylamino-2-imidazolines on a solid support [J].

Genc, M ;

Servi, S .

HETEROATOM CHEMISTRY, 2005, 16 (02) :142-147

[8] Investigations on the influence of halide substituents on the estrogen receptor interaction of 2,4,5-tris(4-hydroxyphenyl)imidazoles [J].

Gust, R ;

Busch, S ;

Keilitz, R ;

Schmidt, K ;

von Rauch, M .

ARCHIV DER PHARMAZIE, 2003, 336 (10) :456-465

[9] Design, synthesis and structure-activity relationship studies of novel 4,4-bis(trifluoromethyl)imidazolines as acyl-CoA: Cholesterol acyltransferase (ACAT) inhibitors and antihypercholesterolemic agents [J].

Li, HY ;

DeLucca, I ;

Boswell, GA ;

Billheimer, JT ;

Drummond, S ;

Gillies, PJ ;

Robinson, C .

BIOORGANIC & MEDICINAL CHEMISTRY, 1997, 5 (07) :1345-1361

[10] Solvent-free microwave organic synthesis as an efficient procedure for green chemistry [J].

Loupy, A .

COMPTES RENDUS CHIMIE, 2004, 7 (02) :103-112

← 1 2 →