Use of Pulmonary Artery Catheter in Coronary Artery Bypass Graft. Costs and Long-Term Outcomes

被引:17
作者
Xu, Fei [1 ,2 ]
Wang, Qian [3 ]
Zhang, Heng [2 ,4 ]
Chen, Sipeng [5 ]
Ao, Hushan [1 ,2 ]
机构
[1] Chinese Acad Med Sci, Dept Anesthesiol, Cardiovasc Inst, Beijing 100730, Peoples R China
[2] Chinese Acad Med Sci, Fuwai Hosp, Beijing 100730, Peoples R China
[3] Inner Mongolia Med Univ, Dept Anesthesiol, Huhhot Inner Mongolia, Peoples R China
[4] Chinese Acad Med Sci, Dept Cardiothorac Surg, Cardiovasc Inst, Beijing 100730, Peoples R China
[5] Capital Med Univ, Dept Biostat Unit, Beijing, Peoples R China
关键词
CRITICALLY-ILL PATIENTS; CONTROLLED TRIAL; CARE;
D O I
10.1371/journal.pone.0117610
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background Pulmonary artery catheters (PAC) are used widely to monitor hemodynamics in patients undergoing coronary bypass graft (CABG) surgery. However, recent studies have raised concerns regarding both the effectiveness and safety of PAC. Therefore, our aim was to determine the effects of the use of PAC on the short- and long-term health and economic outcomes of patients undergoing CABG. Methods 1361 Chinese patients who consecutively underwent isolated, primary CABG at the Cardiovascular Institute of Fuwai Hospital from June 1, 2012 to December 31, 2012 were included in this study. Of all the patients, 453 received PAC during operation (PAC group) and 908 received no PAC therapy (control group). Short-term and long-term mortality and major complications were analyzed with multivariate regression analysis and propensity score matched-pair analysis was used to yield two well-matched groups for further comparison. Results The patients who were managed with PAC more often received intraoperative vasoactive drugs dopamine (70.9% vs. 45.5%; P<0.001) and epinephrine (7.7% vs. 2.6%; P<0.001). In addition, costs for initial hospitalization were higher for PAC patients ($14,535 vs. $13,873, respectively, p = 0.004). PAC use was neither associated with the perioperative mortality or major complications, nor was it associated with long-term mortality and major adverse cardiac and cerebrovascular events. In addition, comparison between two well-matched groups showed no significant differences either in baseline characteristics or in short- term and long-term outcomes. Conclusions There is no clear indication of any benefit or harm in managing CABG patients with PAC. However, use of PAC in CABG is more expensive. That is, PAC use increased costs without benefit and thus appears unjustified for routine use in CABG surgery.
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页数:11
相关论文
共 25 条
[1]  
Am Soc Anesthesiologists Task Forc, 2003, ANESTHESIOLOGY, V99, P988
[2]  
[Anonymous], 1997, CRIT CARE MED
[3]  
BROHET CR, 1989, J ELECTROCARDIOL, V22, P158
[4]   Pulmonary artery flotation catheters - A statement by the American College of Chest Physicians and the American Thoracic Society [J].
Chernow, B .
CHEST, 1997, 111 (02) :261-262
[5]   The effectiveness of right heart catheterization in the initial care of critically ill patients [J].
Connors, AF ;
Speroff, T ;
Dawson, NV ;
Thomas, C ;
Harrell, FE ;
Wagner, D ;
Desbiens, N ;
Goldman, L ;
Wu, AW ;
Califf, RM ;
Fulkerson, WJ ;
Vidaillet, H ;
Broste, S ;
Bellamy, P ;
Lynn, J ;
Knaus, WA .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1996, 276 (11) :889-897
[6]   PULMONARY-ARTERY CATHETERIZATION - AN ASSESSMENT OF RISKS AND BENEFITS IN 220 SURGICAL PATIENTS [J].
DAVIES, MJ ;
CRONIN, KD ;
DOMAINGUE, CM .
ANAESTHESIA AND INTENSIVE CARE, 1982, 10 (01) :9-14
[7]   Assessment of the clinical effectiveness of pulmonary artery catheters in management of patients in intensive care (PAC-Man): a randomised controlled trial [J].
Harvey, S ;
Harrison, DA ;
Singer, M ;
Ashcroft, J ;
Jones, CM ;
Elbourne, D ;
Brampton, W ;
Williams, D ;
Young, D ;
Rowan, K .
LANCET, 2005, 366 (9484) :472-477
[8]  
Iantorno Micaela, 2012, Acute Card Care, V14, P125, DOI 10.3109/17482941.2012.741245
[9]   The appropriateness of the pulmonary artery catheter in cardiovascular surgery [J].
Jacka, MJ ;
Cohen, MM ;
To, T ;
Devitt, JH ;
Byrick, R .
CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2002, 49 (03) :276-282
[10]   Current Use of the Pulmonary Artery Catheter in Cardiac Surgery: A Survey Study [J].
Judge, Onkar ;
Ji, Fuhai ;
Fleming, Neal ;
Liu, Hong .
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 2015, 29 (01) :69-75