Blue green alga mediated synthesis of gold nanoparticles and its antibacterial efficacy against Gram positive organisms

被引:135
作者
Suganya, K. S. Uma [1 ]
Govindaraju, K. [1 ]
Ganesh Kumar, V. [1 ]
Dhas, T. Stalin [1 ]
Karthick, V. [1 ]
Singaravelu, G. [2 ]
Elanchezhiyan, M. [3 ]
机构
[1] Sathyabama Univ, Ctr Ocean Res, Madras 600119, Tamil Nadu, India
[2] Thiruvalluvar Univ, Nanosci Div, Dept Zool, Vellore 632115, Tamil Nadu, India
[3] Univ Madras, Dr ALM Post Grad Inst Basic Med Sci, Dept Microbiol, Madras 600113, Tamil Nadu, India
来源
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2015年 / 47卷
关键词
Spirulina platensis; Biofunctionalization; Gold nanoparticles; Gram positive organisms; Antibacterial activity; SILVER-NANOPARTICLES; SPIRULINA-PLATENSIS; ESCHERICHIA-COLI; SHAPE; BIOSYNTHESIS; EXTRACT;
D O I
10.1016/j.msec.2014.11.043
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Biofunctionalized gold nanoparticles (AuNPs) play an important role in design and development of nanomedicine. Synthesis of AuNPs from biogenic materials is environmentally benign and possesses high bacterial inhibition and bactericidal properties. In the present study, blue green alga Spirulina platensis protein mediated synthesis of AuNPs and its antibacterial activity against Gram positive bacteria is discussed. AuNPs were characterized using Ultraviolet-visible (UV-vis) spectroscopy, Fluorescence spectroscopy, Fourier Transform-Infrared (FTIR) spectroscopy, Raman spectroscopy, High Resolution-Transmission Electron Microscopy (HR-TEM) and Energy Dispersive X-ray analysis (EDAX). Stable, well defined AuNPs of smaller and uniform shape with an average size of similar to 5 nm were obtained. The antibacterial efficacy of protein functionalized AuNPs were tested against Gram positive organisms Bacillus subtilis and Staphylococcus aureus. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码:351 / 356
页数:6
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