Highly Enantioselective Cobalt-Catalyzed Hydrosilylation of Alkenes

被引：176

作者：

Cheng, Biao ^{[1
]}

Lu, Peng ^{[1
]}

Zhang, Heyi ^{[1
]}

Cheng, Xinpeng ^{[1
]}

Lu, Zhan ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310058, Zhejiang, Peoples R China

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2017年 / 139卷 / 28期

关键词：

CROSS-COUPLING REACTIONS; SILICON BOND FORMATION; ASYMMETRIC HYDROSILYLATION; ORGANIC-SYNTHESIS; INTRAMOLECULAR HYDROSILATION; MARKOVNIKOV HYDROSILYLATION; COMPLEXES; SILANES; OLEFINS; LIGANDS;

D O I：

10.1021/jacs.7b04137

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A cobalt-catalyzed highly Markovnikov-type and enantioselective hydrosilylation of alkenes is developed for the efficient synthesis of valuable chiral dihydrosilanes. This protocol is operationally simple and atom-economy, and using relatively simple and readily available starting materials. The reaction is suitable for both aryl and aliphatic alkenes with excellent functional group tolerability. The reaction could be easily carried out in a gram-scale. The TOF and TON is up to 1800 and 860, respectively.

引用

页码：9439 / 9442

页数：4

共 50 条

[41] Cobalt Complex-Catalyzed Hydrosilylation of Alkenes and Alkynes
Sun, Jian
Deng, Liang
ACS CATALYSIS, 2016, 6 (01): : 290 - 300
[42] Cobalt-Catalyzed Enantioselective Hydroboration of α-Substituted Acrylates
Patil, Manoj D.
Ghosh, Kiron Kumar
Rajanbabu, T. V.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 146 (10) : 6604 - 6617
[43] Highly asymmetric cobalt-catalyzed aziridination of alkenes with trichloroethoxysulfonyl azide (TcesN3)
Subbarayan, Velusamy
Ruppel, Joshua V.
Zhu, Shifa
Perman, Jason A.
Zhang, X. Peter
CHEMICAL COMMUNICATIONS, 2009, (28) : 4266 - 4268
[44] Regioselective Cobalt-Catalyzed Addition of Sulfides to Unactivated Alkenes
Girijavallabhan, Vinay
Alvarez, Carmen
Njoroge, F. George
JOURNAL OF ORGANIC CHEMISTRY, 2011, 76 (15): : 6442 - 6446
[45] Highly chemoselective cobalt catalyst for the hydrosilylation and hydroboration of alkenes
Ibrahim, Abdulrahman
Entsminger, Steven
Fout, Alison
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
[46] Ligand-controlled regiodivergence in cobalt-catalyzed hydrosilylation of isoprene
Yang, Sa-Na
Liu, Chang-Hui
He, Li-Bowen
Zheng, Hao
Kuai, Chang-Sheng
Wan, Boshun
Ji, Ding-Wei
Chen, Qing-An
ORGANIC CHEMISTRY FRONTIERS, 2023, 10 (09): : 2204 - 2210
[47] Cobalt-Catalyzed Hydrosilylation/Cyclization of 1,6-Enynes
Xi, Tuo
Lu, Zhan
JOURNAL OF ORGANIC CHEMISTRY, 2016, 81 (19): : 8858 - 8866
[48] Cobalt-Catalyzed Hydroalkylation of Alkenes and Alkynes: Advantages and Opportunities
Liu, Bingxue
Liu, Qiang
CHEMCATCHEM, 2024, 16 (01)
[49] Cobalt-Catalyzed Intramolecular Cycloadditions of Alkenylidenecyclopropanes with Alkenes and Dienes
da Concepcion, Eduardo
Fernandez, Israel
Mascarenas, Jose L.
Lopez, Fernando
ADVANCED SYNTHESIS & CATALYSIS, 2024, 366 (04) : 762 - 767
[50] Cobalt-Catalyzed Z-Selective Hydrosilylation of Terminal Alkynes
Teo, Wei Jie
Wang, Chao
Tan, Ye Wei
Ge, Shaozhong
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 56 (15) : 4328 - 4332

← 1 2 3 4 5 →