Alkalization of wall paint prevents airborne contact dermatitis in patients with sensitization to isothiazolinones

被引：5

作者：

Braun-Falco, M. ^{[1
,2
]}

Knott, E. ^{[1
]}

Huss-Marp, J. ^{[1
]}

Ring, J. ^{[1
]}

Hofmann, H. ^{[1
]}

机构：

[1] Tech Univ Munich, Klin & Poliklin Dermatol & Allergol Biederstein, Dept Dermatol & Allergol Biederstein, D-80802 Munich, Germany

[2] Univ Med Ctr Freiburg, Dept Dermatol, D-79104 Freiburg, Germany

来源：

CONTACT DERMATITIS | 2008年 / 59卷 / 02期

关键词：

contact allergy; contact dermatitis; cosmetics; Kathon CG; MCI/; MI; methylchloroisothiazolinone; methylisothiazolinone;

D O I：

10.1111/j.1600-0536.2008.01356.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Isothiazolinones are widely used as preservatives in water- based paint, in particular, the combination of methylchloroisothiazolinone ( MCI) and methylisothiazolinone ( MI) commercially available as Kathon CG, Euxyl K100 , or Acticide among others ( 1). MCI/ MI is known as a highly potent contact allergen and can provoke airborne contact dermatitis after exposure in freshly painted rooms. Because the sensitivity rate to MCI/ MI remains relatively high among patch- tested individuals with 2 - 2.5% despite limiting its concentration in products ( 2), the number of individuals with airborne reactions to wall paint is increasing ( 1, 3, 4). To prevent this reaction, the paint industry developedpreservative- free paint. This preservative- free paint was tested for tolerability in individuals with known airborne contact dermatitis to isothiazolinonepreserved wall paint.

引用

页码：129 / U15

页数：3

共 7 条

[1] Airborne contact dermatitis from methylchloroisothiazolinone in wall paint. Abolition of symptoms by chemical allergen inactivation [J].