Impact of lower limb lymphedema on quality of life in gynecologic cancer survivors after pelvic lymph node dissection

被引:61
作者
Kim, Se Ik [1 ,2 ]
Lim, Myong Cheol [1 ,3 ]
Lee, Jeong Seon [1 ]
Lee, Yumi [1 ]
Park, KiByung [4 ]
Joo, Jungnam [4 ]
Seo, Sang-Soo [1 ]
Kang, Sokbom [1 ,3 ]
Chung, Seung Hyun [5 ]
Park, Sang-Yoon [1 ,3 ]
机构
[1] Res Inst & Hosp, Natl Canc Ctr, Ctr Uterine Canc, Goyang Si 410769, Gyeonggi Do, South Korea
[2] Seoul Natl Univ, Coll Med, Dept Obstet & Gynecol, Seoul, South Korea
[3] Res Inst & Hosp, Natl Canc Ctr, Gynecol Canc Branch, Goyang Si 410769, Gyeonggi Do, South Korea
[4] Res Inst & Hosp, Natl Canc Ctr, Biometr Res Branch, Goyang Si 410769, Gyeonggi Do, South Korea
[5] Res Inst & Hosp, Natl Canc Ctr, Rehabil Med, Goyang Si 410769, Gyeonggi Do, South Korea
关键词
Gynecologic cancer; Lymphedema; Quality of life; LOWER-EXTREMITY LYMPHEDEMA; KOREAN VERSION; ENDOMETRIAL; PREVALENCE; WOMEN; QUESTIONNAIRE; SYMPTOMS; DISTRESS; RISK;
D O I
10.1016/j.ejogrb.2015.06.011
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To evaluate the impact of lower limb lymphedema (LLL) on quality of life (QOL) in cervical, ovarian, and endometrial cancer survivors after pelvic lymph node dissection. Study design: A cross-sectional case-control study was performed using the Korean version of the Gynecologic Cancer Lymphedema Questionnaire (GCLQ-K) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30). In total, 25 women with LLL and 28 women without LLL completed both questionnaires. Results: The GCLQ-K total symptom score and scores for swelling-general, swelling-limb, and heaviness were significantly higher in the LLL group than in the control group. In the EORTC QLQ-C30, the LLL group reported more financial difficulties compared to the control group (mean score, 16.0 vs. 6.0; P = 0.035). Global health status was poorer in the LLL group with borderline statistical significance (mean score, 62.7 vs. 71.4; P = 0.069). Spearman's correlations suggested that global health status in the EORTC QLQ-C30 correlated with the GCLQ-K total symptom score (in the LLL group, R = -0.64, P = 0.001; in the control group, R = -0.42, P = 0.027). Conclusions: QOL decreases due to LLL-related symptoms and financial difficulty in women with LLL. Well-designed prospective studies are required to confirm these findings. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:31 / 36
页数:6
相关论文
共 28 条
[1]   The incidence of symptomatic lower-extremity lymphedema following treatment of uterine corpus malignancies: A 12-year experience at Memorial Sloan-Kettering Cancer Center [J].
Abu-Rustum, Nadeem R. ;
Alektiar, Kaled ;
Iasonos, Alexia ;
Lev, Gali ;
Sonoda, Yukio ;
Aghajanian, Carol ;
Chi, Dennis S. ;
Barakat, Richard R. .
GYNECOLOGIC ONCOLOGY, 2006, 103 (02) :714-718
[2]   Lymphedema and Quality of Life in Breast Cancer Survivors: The Iowa Women's Health Study [J].
Ahmed, Rehana L. ;
Prizment, Anna ;
Lazovich, DeAnn ;
Schmitz, Kathryn H. ;
Folsom, Aaron R. .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (35) :5689-5696
[3]  
[Anonymous], STUD PHYS FUNCT QUAL
[4]  
[Anonymous], LYMPH SURG PAT END C
[5]   Lymphedema and quality of life in survivors of early-stage breast cancer [J].
Beaulac, SM ;
McNair, LA ;
Scott, TE ;
LaMorte, WW ;
Kavanah, MT .
ARCHIVES OF SURGERY, 2002, 137 (11) :1253-1257
[6]   Lymphedema after gynecological cancer treatment - Prevalence, correlates, and supportive care needs [J].
Beesley, Vanessa ;
Janda, Monika ;
Eakin, Elizabeth ;
Obermair, Andreas ;
Battistutta, Diana .
CANCER, 2007, 109 (12) :2607-2614
[7]   Incidence, risk factors and estimates of a woman's risk of developing secondary lower limb lymphedema and lymphedema-specific supportive care needs in women treated for endometrial cancer [J].
Beesley, Vanessa L. ;
Rowlands, Ingrid J. ;
Hayes, Sandi C. ;
Janda, Monika ;
O'Rourke, Peter ;
Marquart, Louise ;
Quinn, Michael A. ;
Spurdle, Amanda B. ;
Obermair, Andreas ;
Brand, Alison ;
Oehler, Martin K. ;
Leung, Yee ;
McQuire, Lesley ;
Webb, Penelope M. .
GYNECOLOGIC ONCOLOGY, 2015, 136 (01) :87-93
[8]   The Prevalence of Lymphedema Symptoms Among Survivors of Long-term Cancer with or at Risk for Lower Limb Lymphedema [J].
Brown, Justin C. ;
Chu, Christina S. ;
Cheville, Andrea L. ;
Schmitz, Kathryn H. .
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION, 2013, 92 (03) :223-231
[9]   A pilot study using the Gynecologic Cancer Lymphedema Questionnaire (GCLQ) as a clinical care tool to identify lower extremity lymphedema in gynecologic cancer survivors [J].
Carter, Jeanne ;
Raviv, Leigh ;
Appollo, Kathleen ;
Baser, Raymond E. ;
Iasonos, Alexia ;
Barakat, Richard R. .
GYNECOLOGIC ONCOLOGY, 2010, 117 (02) :317-323
[10]   The psychosocial impact of lymphedema-related distress among breast cancer survivors in the WHEL Study [J].
Dominick, Sally A. ;
Natarajan, Loki ;
Pierce, John P. ;
Madanat, Hala ;
Madlensky, Lisa .
PSYCHO-ONCOLOGY, 2014, 23 (09) :1049-1056