Patent foramen ovale: Current pathology, pathophysiology, and clinical status

被引：229
作者：
Hara, H
Virmani, R
Ladich, E
Mackey-Bojack, S
Titus, J
Reisman, M
Gray, W
Nakamura, M
Mooney, M
Poulose, A
Schwartz, RS [1 ]
机构：
[1] Minneapolis Heart Inst & Fdn, Minneapolis, MN USA
[2] Int Registry Pathol, Gaithersburg, MD USA
[3] Jesse E Edwards Registry Cardiovasc Dis, St Paul, MN USA
[4] Swedish Med Ctr, Seattle, WA USA
[5] Toho Univ, Ohashi Hosp, Div Cardiovasc Med, Tokyo, Japan
来源：
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2005年 / 46卷 / 09期
关键词：
D O I：
10.1016/j.jacc.2005.08.038
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Patent foramen ovale (PFO) is experiencing increased clinical interest as a congenital cardiac lesion persisting into adulthood. It is implicated in several serious clinical syndromes, including stroke, myocardial infarction, and systemic embolism. The PFO is now amenable to percutaneous interventional therapies, and multiple novel technologies are either available or under development for lesion closure. The PFO should be better understood to take advantage of emerging percutaneous treatment options. This paper reviews PFO anatomy, pathology, pathophysiology, and clinical impact and discusses current therapeutic options.
引用
收藏
页码：1768 / 1776
页数：9
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