Mesothelial proliferation of the tunica vaginalis testis

被引：0

作者：

Greimelmaier, K. ^{[1
]}

Wohlschlaeger, J. ^{[1
,3
]}

Probst, A. ^{[2
]}

Hager, T. ^{[3
]}

Wardelmann, E. ^{[4
]}

Werlein, C. ^{[5
]}

Jonigk, D. ^{[5
,6
]}

Muelle, K. M. ^{[4
]}

机构：

[1] Diakonissenkrankenhaus Flensburg, Inst Pathol, Knuthstr 1, D-24939 Flensburg, Germany

[2] Diakonissenkrankenhaus Flensburg, Urolog Klin, Flensburg, Germany

[3] Univ Klinikum Essen, Inst Pathol, Essen, Germany

[4] Univ Klinikum Munster, Gerhard Domagk Inst Pathol, Munster, Germany

[5] Hannover Med Sch, Inst Pathol, Hannover, Germany

[6] Biomed Res Endstage & Obstruct Lung Dis Hannover, DZL, Hannover, Germany

来源：

PATHOLOGE | 2020年 / 41卷 / 04期

关键词：

Mesothelial hyperplasia; Hydrocele sac; Malignant mesothelioma; Benign mesothelial proliferation; Tunica vaginalis of the testis; MALIGNANT MESOTHELIOMA; DIAGNOSIS;

D O I：

10.1007/s00292-020-00797-6

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Proliferative changes seen in reactive mesothelial hyperplasia of a hydrocele sac may mimic malignant mesothelioma. There is no immunohistochemical staining that reliably separates benign from malignant mesothelial proliferations. However, the combined analysis of BAP1 by immunohistochemistry and CDKN2A by FISH has been reported to yield both a high specificity and sensitivity in this differential diagnosis. In addition, the evaluation of risk factors such as asbestos exposure or prior traumata may be helpful for the correct diagnosis. Exclusion of stromal invasion, which is diagnostic for malign mesothelioma, is of utmost importance. Therefore, extended histological workup is essential.

引用

页码：406 / 410

页数：5

共 7 条

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