BLOOD LEAD LEVELS IN ANDEAN INFANTS AND YOUNG CHILDREN IN ECUADOR: AN INTERNATIONAL COMPARISON

被引:21
作者
Counter, S. Allen [1 ,2 ]
Buchanan, Leo H. [3 ,4 ]
Ortega, Fernando [5 ,6 ]
机构
[1] Harvard Univ, Sch Med, Dept Neurol, Biol Labs, Cambridge, MA 02138 USA
[2] Massachusetts Gen Hosp, Dept Neurophysiol, Boston, MA 02114 USA
[3] Univ Massachusetts, Sch Med, Dept Pediat, Eunice Kennedy Shriver Ctr, Worcester, MA USA
[4] Harvard Univ Hlth Serv, Dept Otolaryngol, Cambridge, MA USA
[5] Univ San Francisco Quito, Colegio Artes Liberales, Escuela Salud Publ, Colegio Ciencias Salud,Escuela Med, Quito, Ecuador
[6] Univ San Francisco Quito, Galapagos Inst Arts & Sci GAIAS, Quito, Ecuador
来源
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES | 2015年 / 78卷 / 12期
基金
美国国家卫生研究院;
关键词
ZINC PROTOPORPHYRIN LEVELS; RISK-FACTORS; BREAST-MILK; IRON-DEFICIENCY; EXPOSURE; ASSOCIATION; IMPAIRMENT; GASOLINE; NIGERIA; BURDEN;
D O I
10.1080/15287394.2015.1031050
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Lead (Pb) exposure in infants and children remains an international health concern. Blood lead (PbB) levels of a cohort of 130 Ecuadorian infants and young children aged 0.33 to 5.8 yr were compared to values reported for similar age groups in Africa, Asia, Europe, Latin America, and the United States. The mean PbB level for the total group of 130 Ecuadorian infants and young children in this study was 29.4 g/dl (SD: 24.3; range: 3.0-128.2; median: 21.7; geometric mean: 20.7 g/dl). The mean PbB level for the 0-2 yr age group (infants) was 33.6 g/dl (SD: 28.9; median: 22.0; range: 3.9-119.7; geometric mean: 23.6 g/dl), while the average PbB level for the 3-5 yr age group (young children) was 27.9 g/dl (SD: 22.5: median: 22; range: 3-128.2; geometric mean: 19.8 g/dl). The difference between the mean PbB levels for the infants and young children was not statistically significant. The average PbB level of 32.6 g/dl for males was not statistically different from the mean PbB level of 26.3 g/dl for females. The PbB levels observed in Ecuadorian infants and young children in this investigation were elevated above the World Health Organization (WHO) level of concern of 10 g/dl and Centers for Disease Control and Prevention (CDC) current reference value of 5 g/dl. Values were comparable to concentrations found in Pakistan, where occupational use of Pb is prevalent. These findings further indicate that infants and young children exposed to Pb from Pb glazing of ceramics in Andean Ecuadorian villages exhibit greater potential metal-mediated poisoning than children of similar ages in Asia, Europe, other Latin American countries, and the United States.
引用
收藏
页码:778 / 787
页数:10
相关论文
共 60 条
  • [11] ENVIRONMENTAL LEAD EXPOSURE AND OTOACOUSTIC EMISSIONS IN ANDEAN CHILDREN
    Buchanan, Leo H.
    Counter, S. Allen
    Ortega, Fernando
    [J]. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 2011, 74 (19): : 1280 - 1293
  • [12] Carvalho Fernando Martins, 2003, Rev Panam Salud Publica, V13, P19, DOI 10.1590/S1020-49892003000100003
  • [13] Lead levels in new enamel household paints from Asia, Africa and South America
    Clark, C. Scott
    Rampal, Krishna G.
    Thuppil, Venkatesh
    Roda, Sandy M.
    Succop, Paul
    Menrath, William
    Chen, Chin K.
    Adebamowo, Eugenious O.
    Agbede, Oluwole A.
    Sridhar, Mynepalli K. C.
    Adebamowo, Clement A.
    Zakaria, Yehia
    El-Safty, Amal
    Shinde, Rana M.
    Yu, Jiefei
    [J]. ENVIRONMENTAL RESEARCH, 2009, 109 (07) : 930 - 936
  • [14] Counter S A, 2000, Int J Occup Environ Health, V6, P169
  • [15] LEAD LEVELS IN THE BREAST MILK OF NURSING ANDEAN MOTHERS LIVING IN A LEAD-CONTAMINATED ENVIRONMENT
    Counter, S. Allen
    Buchanan, Leo H.
    Ortega, Fernando
    Chiriboga, Roberto
    Correa, Rommy
    Angela Collaguaso, Maria
    [J]. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 2014, 77 (17): : 993 - 1003
  • [16] Neurophysiologic and Neurocognitive Case Profiles of Andean Patients with Chronic Environmental Lead Poisoning
    Counter, S. Allen
    Buchanan, Leo H.
    Ortega, Fernando
    [J]. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 2009, 72 (19): : 1150 - 1159
  • [17] Neurocognitive Screening of Lead-Exposed Andean Adolescents and Young Adults
    Counter, S. Allen
    Buchanan, Leo H.
    Ortega, Fernando
    [J]. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 2009, 72 (10): : 625 - 632
  • [18] Neurocognitive effects of chronic lead intoxication in Andean children
    Counter, SA
    Buchanan, LH
    Rosas, HD
    Ortega, F
    [J]. JOURNAL OF THE NEUROLOGICAL SCIENCES, 1998, 160 (01) : 47 - 53
  • [19] Neurocognitive impairment in lead-exposed children of Andean lead-glazing workers
    Counter, SA
    Buchanan, LH
    Ortega, F
    [J]. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2005, 47 (03) : 306 - 312
  • [20] Current pediatric and maternal lead levels in blood and breast milk in Andean inhabitants of a lead-glazing enclave
    Counter, SA
    Buchanan, LH
    Ortega, F
    [J]. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2004, 46 (09) : 967 - 973