BLOOD LEAD LEVELS IN ANDEAN INFANTS AND YOUNG CHILDREN IN ECUADOR: AN INTERNATIONAL COMPARISON

被引:21
作者
Counter, S. Allen [1 ,2 ]
Buchanan, Leo H. [3 ,4 ]
Ortega, Fernando [5 ,6 ]
机构
[1] Harvard Univ, Sch Med, Dept Neurol, Biol Labs, Cambridge, MA 02138 USA
[2] Massachusetts Gen Hosp, Dept Neurophysiol, Boston, MA 02114 USA
[3] Univ Massachusetts, Sch Med, Dept Pediat, Eunice Kennedy Shriver Ctr, Worcester, MA USA
[4] Harvard Univ Hlth Serv, Dept Otolaryngol, Cambridge, MA USA
[5] Univ San Francisco Quito, Colegio Artes Liberales, Escuela Salud Publ, Colegio Ciencias Salud,Escuela Med, Quito, Ecuador
[6] Univ San Francisco Quito, Galapagos Inst Arts & Sci GAIAS, Quito, Ecuador
来源
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES | 2015年 / 78卷 / 12期
基金
美国国家卫生研究院;
关键词
ZINC PROTOPORPHYRIN LEVELS; RISK-FACTORS; BREAST-MILK; IRON-DEFICIENCY; EXPOSURE; ASSOCIATION; IMPAIRMENT; GASOLINE; NIGERIA; BURDEN;
D O I
10.1080/15287394.2015.1031050
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Lead (Pb) exposure in infants and children remains an international health concern. Blood lead (PbB) levels of a cohort of 130 Ecuadorian infants and young children aged 0.33 to 5.8 yr were compared to values reported for similar age groups in Africa, Asia, Europe, Latin America, and the United States. The mean PbB level for the total group of 130 Ecuadorian infants and young children in this study was 29.4 g/dl (SD: 24.3; range: 3.0-128.2; median: 21.7; geometric mean: 20.7 g/dl). The mean PbB level for the 0-2 yr age group (infants) was 33.6 g/dl (SD: 28.9; median: 22.0; range: 3.9-119.7; geometric mean: 23.6 g/dl), while the average PbB level for the 3-5 yr age group (young children) was 27.9 g/dl (SD: 22.5: median: 22; range: 3-128.2; geometric mean: 19.8 g/dl). The difference between the mean PbB levels for the infants and young children was not statistically significant. The average PbB level of 32.6 g/dl for males was not statistically different from the mean PbB level of 26.3 g/dl for females. The PbB levels observed in Ecuadorian infants and young children in this investigation were elevated above the World Health Organization (WHO) level of concern of 10 g/dl and Centers for Disease Control and Prevention (CDC) current reference value of 5 g/dl. Values were comparable to concentrations found in Pakistan, where occupational use of Pb is prevalent. These findings further indicate that infants and young children exposed to Pb from Pb glazing of ceramics in Andean Ecuadorian villages exhibit greater potential metal-mediated poisoning than children of similar ages in Asia, Europe, other Latin American countries, and the United States.
引用
收藏
页码:778 / 787
页数:10
相关论文
共 60 条
  • [1] Albalak R, 2003, ARCH ENVIRON HEALTH, V58, P172
  • [2] CHRONOLOGICAL TREND IN BLOOD LEAD LEVELS BETWEEN 1976 AND 1980
    ANNEST, JL
    PIRKLE, JL
    MAKUC, D
    NEESE, JW
    BAYSE, DD
    KOVAR, MG
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1983, 308 (23) : 1373 - 1377
  • [3] [Anonymous], 2010, CHILDH LEAD POIS
  • [4] [Anonymous], 2013, MMWR MORB MORTAL WKL
  • [5] [Anonymous], TOX PROF LEAD
  • [6] Anticona C, 2012, REV PANAM SALUD PUBL, V31, P296
  • [7] Bashir M, 2014, MMWR-MORBID MORTAL W, V63, P325
  • [8] Risk Factors for Lead Exposure in Adult Population in Southern Brazil
    Bertin de Almeida Lopes, Ana Carolina
    Navas-Acien, Ana
    Zamoiski, Rachel
    Silbergeld, Ellen Kovner
    Carvalho, Maria de Fatima H.
    Buzzo, Marcia Liane
    Urbano, Mariana Ragassi
    Martins Junior, Airton da Cunha
    Bastos Paoliello, Monica Maria
    [J]. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 2015, 78 (02): : 92 - 108
  • [9] Interpreting and managing blood lead levels of less than 10 μg/dL in children and reducing childhood exposure to lead:: Recommendations of the Centers for Disease Control and Prevention advisory committee on childhood lead poisoning prevention
    Binns, Helen J.
    Campbell, Carla
    Brown, Mary Jean
    [J]. PEDIATRICS, 2007, 120 (05) : E1285 - E1298
  • [10] A Personal Perspective on the Initial Federal Health-Based Regulation to Remove Lead from Gasoline
    Bridbord, Kenneth
    Hanson, David
    [J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 2009, 117 (08) : 1195 - 1201