Cationic Gold Catalyzes ω-Bromination of Terminal Alkynes and Subsequent Hydroaddition Reactions

被引：33
作者：
Leyva-Perez, Antonio [1 ]
Rubio-Marques, Paula [1 ]
Al-Deyab, Salem S. [2 ]
Al-Resayes, Saud I. [2 ]
Corma, Avelino [1 ,2 ]
机构：
[1] Univ Politecn Valencia, Inst Tecnol Quim, Consejo Super Invest Cient, Valencia 46022, Spain
[2] King Saud Univ, Coll Sci, Dept Chem, Riyadh 11451, Saudi Arabia
来源：
ACS CATALYSIS | 2011年 / 1卷 / 06期
关键词：
gold catalysis; aurophilic interactions; terminal alkynes; sigma; pi-bisfunctionalization; bromoalkynes; BOND-FORMING REACTIONS; ONE-POT SYNTHESIS; INTERMOLECULAR HYDROAMINATION; ORGANOGOLD COMPOUNDS; ROOM-TEMPERATURE; LEWIS-ACID; COMPLEXES; ACTIVATION; ACETYLIDES; EFFICIENT;
D O I：
10.1021/cs200168p
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Orthogonal sigma,pi-bisfunctionalization of terminal alkynes can be achieved with a cationic gold complex in catalytic amounts. First, the terminal C-H bond is transformed to the corresponding bromoalkyne which is then activated toward nucleophilic attack. This reactivity correlates with the structural nature of isolated gold-alkyne complexes.
引用
收藏
页码：601 / 606
页数：6
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