Platelets, On Your Marks, Get Set, Migrate!

被引：5

作者：

Bambach, Sarah K. ^{[1
,2
,3
]}

Laemmermann, Tim ^{[1
]}

机构：

[1] Max Planck Inst Immunobiol & Epigenet, Grp Immune Cell Dynam, Freiburg, Germany

[2] IMPRS MCB, Freiburg, Germany

[3] Univ Freiburg, Fac Biol, Freiburg, Germany

来源：

CELL | 2017年 / 171卷 / 06期

关键词：

DEFENSE;

D O I：

10.1016/j.cell.2017.11.026

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The idea that anucleate platelets display autonomous migration has long been viewed with skepticism. Gaertner et al. provide in vivo evidence that platelets undergo active migration at sites of thrombus formation and in inflamed liver sinusoids. Integrin-dependent migration allows platelets to scavenge and bundle fibrin-bound material, including intravascular bacteria.

引用

收藏

页码：1256 / 1258

页数：4

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