Chitosan as a stabilizer and size-control agent for synthesis of porous flower-shaped palladium nanoparticles and their applications on photo-based therapies

被引:61
作者
Thi Tuong Vy Phan [1 ,2 ]
Hoang, Giang [2 ]
Van Tu Nguyen [1 ,2 ]
Thanh Phuoc Nguyen [1 ,2 ]
Kim, Hye Hyun [1 ,2 ]
Mondal, Sudip [2 ]
Manivasagan, Panchanathan [2 ]
Moorthy, Madhappan Santha [2 ]
Lee, Kang Dae [4 ]
Oh, Junghwan [1 ,2 ,3 ]
机构
[1] Pukyong Natl Univ, Interdisciplinary Program Biomed Mech & Elect Eng, Busan 48513, South Korea
[2] Pukyong Natl Univ, Ctr Marine Integrated Biomed Technol, Busan 48513, South Korea
[3] Pukyong Natl Univ, Dept Biomed Engn, Busan 48513, South Korea
[4] Kosin Univ, Dept Otolaryngol Head & Neck Surg, Coll Med, Busan 48513, South Korea
关键词
Green synthesis; Flower-shaped palladium nanoparticles; Chitosan; Photothermal therapy; Photoacoustic imaging; NANOMATERIALS; PLATINUM;
D O I
10.1016/j.carbpol.2018.10.062
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
This study reported a newly developed green synthesis method using chitosan and vitamin C to prepare porous flower-shaped palladium nanoparticles. We found that chitosan not only worked as a stabilizer but also as a sizecontrol agent for the synthesis of these nanoparticles. The growth model of flower-shaped palladium nanoparticles was proposed to interpret mechanistic understanding. The obtained nanoparticles showed good biocompatibility and strong near-infrared absorption. The nanoparticles were successfully demonstrated to be highly efficient for both in vitro photothermal therapy and in vitro photoacoustic imaging.
引用
收藏
页码:340 / 352
页数:13
相关论文
共 32 条
[1]   Synthesis of chitosan-stabilized platinum and palladium nanoparticles and their hydrogenation activity [J].
Adlim, M ;
Abu Bakar, M ;
Liew, KY ;
Ismail, J .
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2004, 212 (1-2) :141-149
[2]   Gold nanoshell photomodification under a single-nanosecond laser pulse accompanied by color-shifting and bubble formation phenomena [J].
Akchurin, Garif ;
Khlebtsov, Boris ;
Akchurin, Georgy ;
Tuchin, Valery ;
Zharov, Vladimir ;
Khlebtsov, Nikolai .
NANOTECHNOLOGY, 2008, 19 (01)
[3]  
[Anonymous], 2016, NAT REV MATER
[4]   Regulatory mechanisms in maintenance and modulation of transmembrane lipid asymmetry: Pathophysiological implications [J].
Bevers, EM ;
Comfurius, P ;
Zwaal, RFA .
LUPUS, 1996, 5 (05) :480-487
[5]   Multimodal tumor-homing chitosan oligosaccharide-coated biocompatible palladium nanoparticles for photo-based imaging and therapy [J].
Bharathiraja, Subramaniyan ;
Nhat Quang Bui ;
Manivasagan, Panchanathan ;
Moorthy, Madhappan Santha ;
Mondal, Sudip ;
Seo, Hansu ;
Nguyen Thanh Phuoc ;
Thi Tuong Vy Phan ;
Kim, Hyehyun ;
Lee, Kang Dae ;
Oh, Junghwan .
SCIENTIFIC REPORTS, 2018, 8
[6]   Nanomaterials and nanoparticles: Sources and toxicity [J].
Buzea, Cristina ;
Pacheco, Ivan I. ;
Robbie, Kevin .
BIOINTERPHASES, 2007, 2 (04) :MR17-MR71
[7]   Palladium-Based Nanomaterials: Synthesis and Electrochemical Applications [J].
Chen, Aicheng ;
Ostrom, Cassandra .
CHEMICAL REVIEWS, 2015, 115 (21) :11999-12044
[8]   Seed-Mediated Synthesis of Palladium Nanorods and Branched Nanocrystals and Their Use as Recyclable Suzuki Coupling Reaction Catalysts [J].
Chen, Yi-Hsiu ;
Hung, Hsiao-Hui ;
Huang, Michael H. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (25) :9114-9121
[9]   Chitosan as stabilizing agent for negatively charged nanoparticles [J].
Collado-Gonzalez, Mar ;
Montalban, Mercedes G. ;
Pena-Garcia, Jorge ;
Perez-Sanchez, Horacio ;
Villora, Gloria ;
Diaz Banos, F. Guillermo .
CARBOHYDRATE POLYMERS, 2017, 161 :63-70
[10]   Size matters: gold nanoparticles in targeted cancer drug delivery [J].
Dreaden, Erik C. ;
Austin, Lauren A. ;
Mackey, Megan A. ;
El-Sayed, Mostafa A. .
THERAPEUTIC DELIVERY, 2012, 3 (04) :457-478