Multidisciplinary management of voluntary pink oleander poisoning: How to estimate the quantities ingested?

被引：2

作者：

Combe, C. ^{[1
]}

Guitton, J. ^{[2
]}

Daude, A. ^{[3
]}

Le Bricon, T. ^{[3
]}

Guibert, N. ^{[4
]}

Bosset, C. ^{[5
]}

Girardot, T. ^{[6
]}

机构：

[1] Ctr Hosp Valence, Serv Pharm, 179 Blvd Marechal Juin, F-26000 Valence, France

[2] Ctr Hosp Lyon Sud, Lab Biochim Toxicol, 165 Chemin Grand Revoyet, F-69310 Pierre Benite, France

[3] Ctr Hosp Valence, Serv Biol Med, 179 Blvd Marechal Juin, F-26000 Valence, France

[4] Ctr AntiPoison Lyon, 162 Ave Lacassagne, F-69003 Lyon, France

[5] Ctr Hosp Valence, Serv Pediat, 179 Blvd Marechal Juin, F-26000 Valence, France

[6] Ctr Hosp Valence, Serv Reanimat Soins Continus, 179 Blvd Marechal Juin, F-26000 Valence, France

来源：

ANNALES PHARMACEUTIQUES FRANCAISES | 2022年 / 80卷 / 01期

关键词：

Pink oleander; Olendrin; Therapeutic; management; YELLOW OLEANDER; RAPID DETECTION; ANTITOXIN;

D O I：

10.1016/j.pharma.2021.04.003

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This is a case of voluntary ingestion of Neriunn oleander leaves in an adolescent requiring the use of atropine and emergency chartering of antidigoxin antibodies (Digifab (R)) due to the difficulty of assessing oleandrin level and associated toxicity. Upon hospital admission, a digoxinemia was performed (0.44 mu g/mL) and the presence of oleandrine was detected. Oleandrin levels at toxic levels may be suspected by a measure of blood digoxin and explain the patient's clinical signs, which could adapt the therapeutic management. (C) 2021 Academie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved.

引用

页码：76 / 80

页数：5

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