Acute encephalopathy with biphasic seizures and late reduced diffusion in a Spanish girl

被引：4

作者：

Garcia-Boyano, Miguel ^{[1
]}

Manuel Caballero-Caballero, Jose ^{[1
]}

Alguacil-Guillen, Marina ^{[1
]}

Baquero-Artigao, Fernando ^{[1
]}

机构：

[1] Hosp Univ La Paz, Madrid, Spain

来源：

BRAIN & DEVELOPMENT | 2020年 / 42卷 / 03期

关键词：

Acute encephalopathy with biphasic seizures and late reduced diffusion; Human herpesvirus-6; Procalcitonin; Proton magnetic resonance spectroscopy;

D O I：

10.1016/j.braindev.2019.12.004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report a case of a 22-month-old Spanish girl who presented acute encephalopathy with biphasic seizures and late reduced diffusion (AESD). Serum procalcitonin (PCT) reached a maximum of 50.5 ng/mL on the first day whereas C-reactive protein (CRP) peaked at 1.21 mg/dL on the second. At the time of discharge, right spastic hemiparesis persisted. MR spectroscopy on day 23 revealed a decrease in N-acetylaspartate and an increase in choline. To our knowledge, we report the first case of AESD in Europe. These findings support the role of PCT and PCT/CRP ratio in the early diagnosis of AESD and correlation of MR spectroscopy findings with neurological outcome. (C) 2019 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

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收藏

页码：307 / 310

页数：4

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