HLA-B27 polymorphism in the Malays

被引:20
作者
Dhaliwal, JS [1 ]
Too, CL
Lisut, M
Lee, YY
Murad, S
机构
[1] Inst Med Res, Allergy & Immunol Res Ctr, Kuala Lumpur 50588, Malaysia
[2] Malaysian Natl Canc Council MAKNA, Kuala Lumpur, Malaysia
来源
TISSUE ANTIGENS | 2003年 / 62卷 / 04期
关键词
allele frequency; HLA-B27; Malay; subtypes;
D O I
10.1034/j.1399-0039.2003.00107.x
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The frequency of ULA-B27 and its subtypes was determined in 878 Malay subjects. Thirty-five of the subjects typed for HLA-A, -B and -DR were found to be positive for HLA-B27. The frequency of this allele in the Malay population was found to be 3.99%. The subtypes observed and their frequencies are: HLA-B*2704 (19.4%), HLA-B*2705 (5.6%), HLA-B*2706 (72.2%) and HLA-B*2707 (2.8%).
引用
收藏
页码:330 / 332
页数:3
相关论文
共 18 条
[1]  
ALEXEEVA L, 1994, J RHEUMATOL, V21, P2298
[2]   ANTIGEN AND HAPLOTYPE FREQUENCIES AT 3 HUMAN-LEUKOCYTE ANTIGEN LOCI (HLA-A, HLA-B, HLA-C) IN THE PAWAIA OF PAPUA-NEW-GUINEA [J].
BHATIA, K ;
PRASAD, ML ;
BARNISH, G ;
KOKI, G .
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY, 1988, 75 (03) :329-340
[3]  
BREWERTON DA, 1973, LANCET, V1, P904
[4]   Spondyloarthropathies in eastern Asia [J].
Feltkamp, TEW ;
Mardjuadi, A ;
Huang, F ;
Chou, CT .
CURRENT OPINION IN RHEUMATOLOGY, 2001, 13 (04) :285-290
[5]   New insights regarding HLA-B27 diversity in the Asian population [J].
García-Fernández, S ;
Gonzalez, S ;
Blanco, AM ;
Martinez-Borra, J ;
Blanco-Gelaz, M ;
López-Vazquez, A ;
López-Larrea, C .
TISSUE ANTIGENS, 2001, 58 (04) :259-262
[6]   HLA-B27 polymorphism and worldwide susceptibility to ankylosing spondylitis [J].
GonzalezRoces, S ;
Alvarez, MV ;
Gonzalez, S ;
Dieye, A ;
Makni, H ;
Woodfield, DG ;
Housan, L ;
Konenkov, V ;
Abbadi, MC ;
Grunnet, N ;
Coto, E ;
LopezLarrea, C .
TISSUE ANTIGENS, 1997, 49 (02) :116-123
[7]   Seronegative spondyloarthropathies and HLA-B27 subtypes: A study in Asian Indians. [J].
Kanga, U ;
Mehra, NK ;
Larrea, CL ;
Lardy, NM ;
Kumar, A ;
Feltkamp, TEW .
CLINICAL RHEUMATOLOGY, 1996, 15 :13-18
[8]   Epidemiology of HLA-B27 and arthritis [J].
Khan, MA .
CLINICAL RHEUMATOLOGY, 1996, 15 :10-12
[9]  
KHAN MA, 1977, J RHEUMATOL, V4, P39
[10]   Update:: the twenty subtypes of HLA-B27 [J].
Khan, MA .
CURRENT OPINION IN RHEUMATOLOGY, 2000, 12 (04) :235-238