Microwave ablation of hepatocellular carcinoma

被引:190
作者
Liang, Ping [1 ]
Wang, Yang [1 ]
机构
[1] Chinese Peoples Liberat Army Gen Hosp, Dept Ultrasound, Beijing 100853, Peoples R China
关键词
microwave ablation; minimally invasive therapy; hepatocellular carcinoma;
D O I
10.1159/000111718
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objective: This article reviews the basic principles, equipment, current therapeutic status and future trends of microwave ablation (MWA) in the treatment of hepatocellular carcinoma (HCC). Methods: All articles published in English on MWA or MWA as a treatment for HCC were identified with a PubMed search from the 1990s through June 2007. Papers were reviewed on the technical advances of MWA equipment and the clinical applications of MWA including indications, techniques, therapeutic outcomes, complications and combination therapies. Results: MWA has several advantages, including high thermal efficiency, higher capability of coagulating blood vessels, faster ablation time, and an improved convention profile. MWA can induce large ablation volumes and yield good local tumor control, especially for small HCC. Larger HCC can also be completely ablated by using more effective antenna or simultaneous application of multiple antennae. Long-term survival comparable to that of surgery was obtained for tumors measuring 4 cm or less. Associated complications appear to be low. Conclusions: MWA is a promising minimally invasive technique for the treatment of HCC. Future advances are warranted to improve the therapeutic efficacy.
引用
收藏
页码:124 / 131
页数:8
相关论文
共 64 条
[1]  
Abe T, 2000, ENDOSCOPY, V32, P598
[2]  
Aramaki M, 2004, HEPATO-GASTROENTEROL, V51, P1784
[3]   A review of coaxial-based interstitial antennas for hepatic microwave ablation [J].
Bertram, John M. ;
Yang, Deshan ;
Converse, Mark C. ;
Webster, John G. ;
Mahvi, David M. .
Critical Reviews in Biomedical Engineering, 2006, 34 (03) :187-213
[4]   Microwave ablation with multiple simultaneously powered small-gauge triaxial antennas: Results from an in vivo swine liver model [J].
Brace, Christopher L. ;
Laeseke, Paul F. ;
Sampson, Lisa A. ;
Frey, Tina M. ;
van der Weide, Daniel W. ;
Lee, Fred T., Jr. .
RADIOLOGY, 2007, 244 (01) :151-156
[5]   Microwave ablation with a single small-gauge triaxial antenna: In vivo porcine liver model [J].
Brace, Christopher L. ;
Laeseke, Paul F. ;
Sampson, Lisa A. ;
Frey, Tina M. ;
van der Weide, Daniel W. ;
Lee, Fred T., Jr. .
RADIOLOGY, 2007, 242 (02) :435-440
[6]   HEPATOCELLULAR-CARCINOMA [J].
COLOMBO, M .
JOURNAL OF HEPATOLOGY, 1992, 15 (1-2) :225-236
[7]   Thermal ablation and high-temperature thermal therapy: Overview of technology and clinical implementation [J].
Diederich, CJ .
INTERNATIONAL JOURNAL OF HYPERTHERMIA, 2005, 21 (08) :745-753
[8]   Minimally invasive treatment of malignant hepatic tumors: At the threshold of a major breakthrough [J].
Dodd, GD ;
Soulen, MC ;
Kane, RA ;
Livraghi, T ;
Lees, WR ;
Yamashita, Y ;
Gillams, AR ;
Karahan, OI ;
Rhim, H .
RADIOGRAPHICS, 2000, 20 (01) :9-27
[9]   Percutaneous sonographically guided microwave coagulation therapy for hepatocellular carcinoma: Results in 234 patients [J].
Dong, BW ;
Liang, P ;
Yu, XL ;
Su, L ;
Yu, DJ ;
Cheng, ZG ;
Zhang, J .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2003, 180 (06) :1547-1555
[10]   Sequential pathological and immunologic analysis of percutaneous microwave coagulation therapy of hepatocellular carcinoma [J].
Dong, BW ;
Zhang, J ;
Liang, P ;
Yu, XL ;
Su, L ;
Yu, DJ ;
Ji, XL ;
Yu, G .
INTERNATIONAL JOURNAL OF HYPERTHERMIA, 2003, 19 (02) :119-133