Does preoperative coronary angioplasty improve perioperative cardiac outcome?

被引:41
作者
Godet, G
Riou, B
Bertrand, M
Fléron, MH
Goarin, JP
Montalescot, G
Coriat, P
机构
[1] Univ Paris 06, AP HP, CHU Pitie Salpetriere, Dept Anesthesiol & Crit Care, Paris, France
[2] Univ Paris 06, AP HP, CHU Pitie Salpetriere, Dept Emergency Med, Paris, France
[3] Univ Paris 06, AP HP, CHU Pitie Salpetriere, Dept Surg, Paris, France
[4] Univ Paris 06, AP HP, CHU Pitie Salpetriere, Dept Cardiol, Paris, France
关键词
D O I
10.1097/00000542-200504000-00008
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Background: Percutaneous coronary intervention (PCI) is performed in patients with coronary artery disease who are undergoing major noncardiac procedures to reduce perioperative cardiac morbidity and mortality. However, the impact of this approach on postoperative outcome remains controversial. Methods: The authors analyzed a cohort of 1,152 patients after abdominal aortic surgery in which 78 patients underwent PCI. A propensity score analysis was performed. Also, using a logistic regression model, the authors determined variables associatcd with a severe postoperative coronary event or a death in patients without PCI. Then, in patients with PCI, they compared the expected and observed outcome. Results: Five variables (age > 75 yr, blood transfusion > 3 units, repeated surgery, preoperative hemodialysis, and previous cardiac failure) independently predicted (with 94% correctly classified) a severe postoperative coronary event, and five variables (age > 75 yr, repeated surgery, previously abnormal ST segment/T waves, previous hypertension, and previous cardiac failure) independently predicted (with 97% correctly classified) postoperative death. In the PCI group, the observed percentages of patients with a severe postoperative coronary event (9.0% [95% confidence interval, 4.4-17.4]) or death (5.1% [95% confidence interval, 2.0-12-5]) were not significantly different from the expected percentages (8.2 and 6.9%, respectively). When ail patients were pooled together, the odds ratios of PCI were not significant. The propensity score analysis provided a similar conclusion. Conclusion: PCI did not seem to limit significantly cardiac risk or death after aortic surgery.
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页码:739 / 746
页数:8
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