Design, Characterisation and Performance of an Improved Portable and Sustainable Low-Field MRI System

被引：19
作者：
de Vos, Bart [1 ]
Parsa, Javad [1 ,2 ]
Abdulrazaq, Zaynab [1 ]
Teeuwisse, Wouter M. [1 ]
Van Speybroeck, Camille D. E. [1 ]
de Gans, Danny H. [3 ]
Remis, Rob F. [4 ]
O'Reilly, Tom [1 ]
Webb, Andrew G. [1 ,4 ]
机构：
[1] Leiden Univ, Med Ctr, Dept Radiol, CJ Gorter Ctr High Field MRI, Leiden, Netherlands
[2] Percuros BV, Leiden, Netherlands
[3] Delft Univ Technol, Dienst Elektron Mech Ontwikkeling DEMO, Delft, Netherlands
[4] Delft Univ Technol, Circuits & Syst, Delft, Netherlands
来源：
FRONTIERS IN PHYSICS | 2021年 / 9卷
基金：
欧盟地平线“2020”;
关键词：
low field MRI; MR hardware; halbach magnet; gradient coil design; RF coil array; RF amplifier; quality control; gradient amplifier; RESONANCE-IMAGING SYSTEM; SHIM COILS; GRADIENT COIL; PERMANENT-MAGNET; HALBACH MAGNET; OPEN-ACCESS; CONSTRUCTION;
D O I：
10.3389/fphy.2021.701157
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
Low-field permanent magnet-based MRI systems are finding increasing use in portable, sustainable and point-of-care applications. In order to maximize performance while minimizing cost many components of such a system should ideally be designed specifically for low frequency operation. In this paper we describe recent developments in constructing and characterising a low-field portable MRI system for in vivo imaging at 50 mT. These developments include the design of i) high-linearity gradient coils using a modified volume-based target field approach, ii) phased-array receive coils, and iii) a battery-operated three-axis gradient amplifier for improved portability and sustainability. In addition, we report performance characterisation of the RF amplifier, the gradient amplifier, eddy currents from the gradient coils, and describe a quality control protocol for the overall system.
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收藏
页数：16
相关论文
共 49 条
[1]   Design of a permanent magnet with a mechanical sweep suitable for variable-temperature continuous-wave and pulsed EPR spectroscopy [J].
Bauer, C. ;
Raich, H. ;
Jeschke, G. ;
Bluemler, P. .
JOURNAL OF MAGNETIC RESONANCE, 2009, 198 (02) :222-227
[2]  
Blümler P, 2016, NEW DEV NMR, V5, P133
[3]   Proposal for a permanent magnet system with a constant gradient mechanically adjustable in direction and strength [J].
Bluemler, Peter .
CONCEPTS IN MAGNETIC RESONANCE PART B-MAGNETIC RESONANCE ENGINEERING, 2016, 46 (01) :41-48
[4]   Comparison of fast field-cycling magnetic resonance imaging methods and future perspectives [J].
Boedenler, Markus ;
de Rochefort, Ludovic ;
Ross, P. James ;
Chanet, Nicolas ;
Guillot, Genevieve ;
Davies, Gareth R. ;
Goesweiner, Christian ;
Scharfetter, Hermann ;
Lurie, David J. ;
Broche, Lionel M. .
MOLECULAR PHYSICS, 2019, 117 (7-8) :832-848
[5]   TEMPORAL AND SPATIAL-ANALYSIS OF FIELDS GENERATED BY EDDY CURRENTS IN SUPERCONDUCTING MAGNETS - OPTIMIZATION OF CORRECTIONS AND QUANTITATIVE CHARACTERIZATION OF MAGNET GRADIENT SYSTEMS [J].
BOESCH, C ;
GRUETTER, R ;
MARTIN, E .
MAGNETIC RESONANCE IN MEDICINE, 1991, 20 (02) :268-284
[6]   Determining complicated winding patterns for shim coils using stream functions and the target-field method [J].
Brideson, MA ;
Forbes, LK ;
Crozier, S .
CONCEPTS IN MAGNETIC RESONANCE, 2002, 14 (01) :9-18
[7]   A whole-body Fast Field-Cycling scanner for clinical molecular imaging studies [J].
Broche, Lionel M. ;
Ross, P. James ;
Davies, Gareth R. ;
Macleod, Mary-Joan ;
Lurie, David J. .
SCIENTIFIC REPORTS, 2019, 9 (1)
[8]   DESIGN AND EVALUATION OF SHIELDED GRADIENT COILS [J].
CARLSON, JW ;
DERBY, KA ;
HAWRYSZKO, KC ;
WEIDEMAN, M .
MAGNETIC RESONANCE IN MEDICINE, 1992, 26 (02) :191-206
[9]   Design and construction of an actively frequency-switchable RF coil for field-dependent Magnetisation Transfer Contrast MRI with fast field-cycling [J].
Choi, Chang-Hoon ;
Hutchison, James M. S. ;
Lurie, David J. .
JOURNAL OF MAGNETIC RESONANCE, 2010, 207 (01) :134-139
[10]  
Chronik BA, 1998, MAGNET RESON MED, V39, P270, DOI 10.1002/mrm.1910390214
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