The Solute-Exclusion Zone: A Promising Application for Mirofluidics

被引:3
作者
Chen, Chi-Shuo [1 ]
Farr, Erik [1 ]
Anaya, Jesse M. [1 ]
Chen, Eric Y-T [1 ,2 ,3 ]
Chin, Wei-Chun [1 ]
机构
[1] Univ Calif, Bioengn Dept, Merced, CA 94343 USA
[2] MicroBase Technol Corp, Bade City 33464, Taoyuan, Taiwan
[3] Chang Gung Univ, Ctr Biomed Engn, Taoyuan 33302, Taiwan
基金
美国国家科学基金会;
关键词
ION-EXCHANGE; WATER; HYDRATION; SURFACES; FORCES;
D O I
10.3390/e17031466
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
While unique phenomena exist at fluid-solid phase intersections, many interfacial phenomena manifest solely on limited scales-i.e., the nm-mu m ranges-which stifles their application potential. Here, we constructed microfluidic chips that utilize the unique long-distance interface effects of the Solute-Exclusion Zone (EZ) phenomenon to mix, separate, and guide samples in desired directions within microfluidic channels. On our "EZ Chip", we utilized the interfacial force generated by EZs to transport specimens across streamlines without the need of an off-chip power source. The advantages of easy-integration, low fabrication cost, and no off-chip energy input make the EZ suitable for independent, portable lab-on-chip system applications.
引用
收藏
页码:1466 / 1476
页数:11
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