Micro-Masonry: Construction of 3D Structures by Microscale Self-Assembly

被引:87
作者
Fernandez, Javier G. [1 ,2 ,3 ]
Khademhosseini, Ali [1 ,2 ,3 ]
机构
[1] Harvard Univ, Brigham & Womens Hosp, Sch Med, Ctr Biomed Engn,Dept Med, Boston, MA 02115 USA
[2] MIT, Harvard Mit Div Hlth Sci & Technol, Cambridge, MA 02139 USA
[3] Harvard Univ, Wyss Inst Biologically Inspired Engn, Boston, MA 02115 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
CELL-LADEN MICROGELS; IN-VITRO; FABRICATION; HYDROGELS; MICROSTRUCTURES; OBJECTS; ARRAYS; LIGHT;
D O I
10.1002/adma.200903893
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A biocompatible method for general construction of 3D structures by aggregation of micrometric polymeric subunits is presented. Shape-controlled microgels are forced to self-assemble, in a structure similar to a brick wall, in different shapes by limiting their movement onto a surface. Scaffolds with high spatial resolution in the aggregation and composed by the addition of multiple layers are produced.
引用
收藏
页码:2538 / 2541
页数:4
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