Predicting responses to chemotherapy in breast cancer: from bench to bedside

被引：0
|
作者：
Akashi-Tanaka, Sadako [1 ]
机构：
[1] Natl Canc Ctr, Div Breast Surg, Chuo Ku, Tokyo 1040045, Japan
来源：
BREAST CANCER | 2010年 / 17卷 / 02期
关键词：
Breast cancer; Predictive factor; Gene expression profile; Chemotherapy; Pharmacogenomics; GENE-EXPRESSION; NEOADJUVANT CHEMOTHERAPY; DOCETAXEL; EFFICACY; THERAPY; TRASTUZUMAB; SUBTYPES; MARKER; WOMEN; TRIAL;
D O I：
10.1007/s12282-009-0166-0
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Recent progress in biotechnology, notably microarray analyses, makes it possible to examine the genome-based characteristics of tumors with different prognoses and predict responses to chemotherapy. Furthermore, pharmacogenomic techniques are expected to predict the optimal regimen for individual patients that will provide high benefits with reduced toxicity. Some predictive or prognostic tests for breast cancer are now moving from bench to bedside.
引用
收藏
页码：92 / 96
页数：5
相关论文
共 50 条
  • [41] From bench to bedside: Future potential for the translation of prolactin inhibitors as breast cancer therapeutics
    Clevenger, Charles V.
    Zheng, Jiamao
    Jablonski, Elizabeth M.
    Galbaugh, Traci L.
    Fang, Feng
    JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 2008, 13 (01) : 147 - 156
  • [42] Sonic Hedgehog in pancreatic cancer: From bench to bedside, then back to the bench
    Rosow, David E.
    Liss, Andrew S.
    Strobel, Oliver
    Fritz, Stefan
    Bausch, Dirk
    Valsangkar, Nakul P.
    Alsina, Janivette
    Kulemann, Birte
    Park, Joo Kyung
    Yamaguchi, Junpei
    LaFemina, Jennifer
    Thayer, Sarah P.
    SURGERY, 2012, 152 (03) : S19 - S32
  • [43] The Risk of Toxicities from Trastuzumab, Alone or in Combination, in an Elderly Breast Cancer Population
    Adamo, Vincenzo
    Ricciardi, Giuseppina Rosaria Rita
    Adamo, Barbara
    Ferraro, Giuseppa
    Franchina, Tindara
    Rossello, Rosalba
    Zanghi, Mariangela
    Cicero, Giuseppe
    Rizzo, Sergio
    Caristi, Nicola
    Russo, Antonio
    ONCOLOGY, 2014, 86 (01) : 16 - 21
  • [44] From Bench to Bedside: Future Potential for the Translation of Prolactin Inhibitors as Breast Cancer Therapeutics
    Charles V. Clevenger
    Jiamao Zheng
    Elizabeth M. Jablonski
    Traci L. Galbaugh
    Feng Fang
    Journal of Mammary Gland Biology and Neoplasia, 2008, 13 : 147 - 156
  • [45] Cardiotoxicity of Breast Cancer Chemotherapy
    Roberts, Sacha A.
    Frishman, William H.
    CARDIOLOGY IN REVIEW, 2025, 33 (02) : 109 - 111
  • [46] Tumour-infiltrating CD8 to FOXP3 lymphocyte ratio in predicting treatment responses to neoadjuvant chemotherapy of aggressive breast cancer
    Asano, Y.
    Kashiwagi, S.
    Goto, W.
    Kurata, K.
    Noda, S.
    Takashima, T.
    Onoda, N.
    Tanaka, S.
    Ohsawa, M.
    Hirakawa, K.
    BRITISH JOURNAL OF SURGERY, 2016, 103 (07) : 845 - 854
  • [47] Is Adjuvant Chemotherapy Useful for Women With Luminal A Breast Cancer?
    Coates, Alan S.
    Colleoni, Marco
    Goldhirsch, Aron
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (12) : 1260 - 1263
  • [48] Noninvasive Artificial Intelligence System for Early Predicting Residual Cancer Burden During Neoadjuvant Chemotherapy in Breast Cancer
    Li, Wei
    Huang, Yu-Hong
    Zhu, Teng
    Zhang, Yi-Min
    Zheng, Xing-Xing
    Zhang, Ting-Feng
    Lin, Ying-Yi
    Wu, Zhi-Yong
    Liu, Zai-Yi
    Lin, Ying
    Ye, Guo-Lin
    Wang, Kun
    ANNALS OF SURGERY, 2025, 281 (04) : 645 - 654
  • [49] From bench to bedside: Advancing liposomal doxorubicin for targeted cancer therapy
    Ahmad, Mohammad Zaki
    Mustafa, Gulam
    Abdel-Wahab, Basel A.
    Pathak, Kalyani
    Das, Aparoop
    Sahariah, Jon Jyoti
    Kalita, Parimita
    Alam, Afroze
    Borthakur, Partha Protim
    RESULTS IN SURFACES AND INTERFACES, 2025, 19
  • [50] Meta-analysis of the association of breast cancer subtype and pathologic complete response to neoadjuvant chemotherapy
    Houssami, Nehmat
    Macaskill, Petra
    von Minckwitz, Gunter
    Marinovich, Michael L.
    Mamounas, Eleftherios
    EUROPEAN JOURNAL OF CANCER, 2012, 48 (18) : 3342 - 3354
12345