The use of low-intensity ultrasound to accelerate the healing of fractures

被引:294
作者
Rubin, C [1 ]
Bolander, M
Ryaby, JP
Hadjiargyrou, M
机构
[1] SUNY Stony Brook, Dept Biomed Engn, Stony Brook, NY 11794 USA
[2] Mayo Clin & Mayo Fdn, Dept Orthoped, Rochester, MN 55905 USA
[3] Exogen Inc, Piscataway, NJ 08855 USA
关键词
D O I
10.2106/00004623-200102000-00015
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Double-blind, prospective, placebo-controlled clinical trials demonstrate that healing times of fresh fractures of the radius and tibia are reduced by up to 40% with the use of low-intensity ultrasound. Animal studies indicate that low-intensity ultrasound exposure results in stronger and stiffer callus formation and in acceleration of the endochondral ossification process. Extensive clinical evidence demonstrates that ultrasound represents a safe, noninvasive method of accelerating the healing of fresh fractures of the tibia, the distal aspect of the radius, the scaphoid, and the metatarsals. Clinical studies indicate that ultrasound reduces the confounding effect of smoking and patient age on the fracture-healing process. Ultrasound requires a brief, twenty-minute, daily at-home treatment regimen and has no known contraindications. The effectiveness of low-intensity ultrasound has also been demonstrated in the clinical treatment of delayed unions and nonunions.
引用
收藏
页码:259 / 270
页数:12
相关论文
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