Stem cell based therapies for spinal cord injury

被引：59
作者：
Muheremu, Aikeremujiang [1 ,2 ,3 ]
Peng, Jiang [2 ]
Ao, Qiang [3 ]
机构：
[1] Xinjiang Med Univ, Affiliated Hosp 6, Dept Spine Surg, 118 Henan West St, Urumqi, Xinjiang, Peoples R China
[2] Peoples Liberat Army, Gen Hosp, Inst Orthopaed, 28 Fuxing Rd, Beijing 100853, Peoples R China
[3] China Med Univ, Dept Tissue Engn, Shenyang North New Area, 77 Puhe Rd, Shenyang 112011, Liaoning Provin, Peoples R China
来源：
TISSUE & CELL | 2016年 / 48卷 / 04期
基金：
国家高技术研究发展计划(863计划);
关键词：
Stem cell; Transplantation; Spinal cord injury; FUNCTIONAL RECOVERY; AXONAL GROWTH; TISSUE-DAMAGE; TRANSPLANTATION; REPAIR; GENERATION; NEURONS; MODEL; SAFE; OVEREXPRESSION;
D O I：
10.1016/j.tice.2016.05.008
中图分类号：
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号：
100101 ;
摘要：
Treatment of spinal cord injury has always been a challenge for clinical practitioners and scientists. The development in stem cell based therapies has brought new hopes to patients with spinal cord injuries. In the last a few decades, a variety of stem cells have been used to treat spinal cord injury in animal experiments and some clinical trials. However, there are many technical and ethical challenges to overcome before this novel therapeutic method can be widely applied in clinical practice. With further research in pluripotent stem cells and combined application of genetic and tissue engineering techniques, stem cell based therapies are bond to play increasingly important role in the management of spinal cord injuries. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码：328 / 333
页数：6
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