Alveolar proteinosis in Behcet's disease

被引：1

作者：

Tetikkurt, Cuneyt ^{[1
]}

Tetikkurt, Seza ^{[2
]}

Ozdemir, Imran ^{[1
]}

Zuhur, Cigdem ^{[1
]}

Bayar, Nihal ^{[1
]}

机构：

[1] Istanbul Univ, Cerrahpasa Med Fac, Dept Pulm Dis, TR-34303 Istanbul, Turkey

[2] Taksim Res & Training Hosp, Dept Pathol, Istanbul, Turkey

来源：

MULTIDISCIPLINARY RESPIRATORY MEDICINE | 2010年 / 5卷 / 04期

关键词：

Alveolar proteinosis; anti-granulocyte-macrophage colony stimulating antibody; Behcet's disease; PATHOGENESIS; DIAGNOSIS;

D O I：

10.1186/2049-6958-5-4-264

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

A 51-year-old man with Behcet's disease complained of fever, dry cough and dyspnea during exertion. Chest CT showed ground glass opacities with interstitial septal thickening in both lungs. Bronchoalveolar lavage (BAL) revealed amorphous and lipoproteinaceous material that was periodic acid-Schiff (PAS) stain positive. Transbronchial biopsy specimen demonstrated PAS positive alveolar eosinophilic material consistent with pulmonary alveolar proteinosis. Serum anti-granulocyte-macrophage colony stimulating factor (GM-CSF) antibody was negative. Recent studies have reported anti-GM-CSF not present in the the serum of patients with secondary pulmonary alveolar proteinosis (PAP) but they have not reported so in patients with idiopathic PAP. We report a case of alveolar proteinosis in the setting of Behcet's disease with spontaneous remission.

引用

页码：264 / 266

页数：3

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