Gut microbiota and obesity: New insights

被引：31
作者：
Sarmiento-Andrade, Yoredy [1 ]
Suarez, Rosario [1 ]
Quintero, Beatriz [1 ]
Garrochamba, Kleber [2 ]
Chapela, Sebastian Pablo [3 ,4 ]
机构：
[1] Univ Tecn Particular Loja, Sch Med, Loja, Ecuador
[2] Univ Tecn Particular Loja, Dept Hlth Sci, Loja, Ecuador
[3] Univ Buenos Aires, Fac Ciencias Med, Dept Bioquim Humana, Buenos Aires, DF, Argentina
[4] Hosp Britan Buenos Aires, Nutr Support Team, Buenos Aires, DF, Argentina
来源：
FRONTIERS IN NUTRITION | 2022年 / 9卷
关键词：
obesity; gut; microbiota; microbiome; overweight; PEPTIDE CLEARANCE RECEPTOR; GASTRIC BYPASS-SURGERY; HIGH-FAT DIET; ADIPOSE-TISSUE; INSULIN SENSITIVITY; GLUCOSE-INTOLERANCE; METABOLIC SYNDROME; WEIGHT-LOSS; OVERWEIGHT; PROBIOTICS;
D O I：
10.3389/fnut.2022.1018212
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Obesity is a pathology whose incidence is increasing throughout the world. There are many pathologies associated with obesity. In recent years, the influence of the microbiota on both health and pathological states has been known. There is growing information related to changes in the microbiome and obesity, as well as its associated pathologies. Changes associated with age, exercise, and weight changes have been described. In addition, metabolic changes associated with the microbiota, bariatric surgery, and fecal matter transplantation are described. In this review, we summarize the biology and physiology of microbiota in obese patients, its role in the pathophysiology of several disorders associated, and the emerging therapeutic applications of prebiotics, probiotics, and fecal microbiota transplantation.
引用
收藏
页数：12
相关论文
共 101 条
[1]   Is BMI the best measure of obesity? [J].
Adab, Peymane ;
Pallan, Miranda ;
Whincup, Peter H. .
BMJ-BRITISH MEDICAL JOURNAL, 2018, 360
[2]  
Allen JM, 2018, MED SCI SPORT EXER, V50, P747, DOI [10.1249/MSS.0000000000001495, 10.1249/mss.0000000000001495]
[3]  
Apovian Caroline M, 2016, Am J Manag Care, V22, ps176
[4]   A predictive regression model of the obesity-related inflammatory status based on gut microbiota composition [J].
Aranaz, Paula ;
Ramos-Lopez, Omar ;
Cuevas-Sierra, Amanda ;
Martinez, J. Alfredo ;
Milagro, Fermin I. ;
Riezu-Boj, Jose I. .
INTERNATIONAL JOURNAL OF OBESITY, 2021, 45 (10) :2261-2268
[5]   Major microbiota dysbiosis in severe obesity: fate after bariatric surgery [J].
Aron-Wisnewsky, Judith ;
Prifti, Edi ;
Belda, Eugeni ;
Ichou, Farid ;
Kayser, Brandon D. ;
Dao, Maria Carlota ;
Verger, Eric O. ;
Hedjazi, Lyamine ;
Bouillot, Jean-Luc ;
Chevallier, Jean-Marc ;
Pons, Nicolas ;
Le Chatelier, Emmanuelle ;
Levenez, Florence ;
Ehrlich, Stanislav Dusko ;
Dore, Joel ;
Zucker, Jean-Daniel ;
Clement, Karine .
GUT, 2019, 68 (01) :70-82
[6]   Bacterial Microbiota and Fatty Acids in the Faeces of Overweight and Obese Children [J].
Barczynska, Renata ;
Litwin, Mieczyslaw ;
Slizewska, Katarzyna ;
Szalecki, Mieczyslaw ;
Berdowska, Agnieszka ;
Bandurska, Katarzyna ;
Libudzisz, Zdzislawa ;
Kapusniak, Janusz .
POLISH JOURNAL OF MICROBIOLOGY, 2018, 67 (03) :339-345
[7]   GUT MICROBIOTA, PREBIOTICS, PROBIOTICS, AND SYNBIOTICS IN ANAGEMENT OF OBESITY AND PREDIABETES: REVIEW OF RANDOMIZED CONTROLLED TRIALS [J].
Barengolts, Elena .
ENDOCRINE PRACTICE, 2016, 22 (10) :1224-1234
[8]   A randomised controlled trial of a probiotic and a prebiotic examining metabolic and mental health outcomes in adults with pre-diabetes [J].
Barthow, Christine ;
Hood, Fiona ;
Crane, Julian ;
Huthwaite, Mark ;
Weatherall, Mark ;
Parry-Strong, Amber ;
Krebs, Jeremy .
BMJ OPEN, 2022, 12 (03)
[9]   Projection of Gut Microbiome Pre- and Post-Bariatric Surgery To Predict Surgery Outcome [J].
Ben Izhak, Meirav ;
Eshel, Adi ;
Cohen, Ruti ;
Madar-Shapiro, Liora ;
Meiri, Hamutal ;
Wachtel, Chaim ;
Leung, Conrad ;
Messick, Edward ;
Jongkam, Narisra ;
Mavor, Eli ;
Sapozhnikov, Shimon ;
Maharshak, Nitsan ;
Abu-Abeid, Subhi ;
Alis, Avishai ;
Mahler, Ilanit ;
Meoded, Aviel ;
Eldar, Shai Meron ;
Koren, Omry ;
Louzoun, Yoram .
MSYSTEMS, 2021, 6 (03)
[10]   Effects of prebiotics on postprandial GLP-1, GLP-2 and glucose regulation in patients with type 2 diabetes: A randomised, double-blind, placebo-controlled crossover trial [J].
Birkeland, Eline ;
Gharagozlian, Sedegheh ;
Gulseth, Hanne L. ;
Birkeland, Kare, I ;
Hartmann, Bolette ;
Holst, Jens J. ;
Holst, Rene ;
Aas, Anne-Marie .
DIABETIC MEDICINE, 2021, 38 (10)
12345678910