Supramolecular Chemistry: Induced Circular Dichroism to Study Host-Guest Geometry

被引：22

作者：

Mendicuti, Francisco ^{[1
]}

Jose Gonzalez-Alvarez, Maria ^{[1
]}

机构：

[1] Univ Alcala de Henares, Dept Quim Fis, Madrid 28871, Spain

来源：

JOURNAL OF CHEMICAL EDUCATION | 2010年 / 87卷 / 09期

关键词：

BETA-CYCLODEXTRIN COMPLEXES; INCLUSION COMPLEXES; GAMMA-CYCLODEXTRIN; ALPHA-CYCLODEXTRIN; GENERAL RULE; FLUORESCENCE;

D O I：

10.1021/ed100276q

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this laboratory experiment, students obtain information about the structure of a host-guest complex from the interpretation of circular dichroism measurements. The value and sign of the induced circular dichroism (ICD) on an achiral chromophore guest when it complexes with a cyclodextrin can be related to the guest penetration and its orientation relative to the cyclodextrin. This experiment examines the complexation of dimethyl 2,3-naphthalenedicarboxylate with 2-hydroxypropyl-α-, -β-, and -γ-cyclodextrins in aqueous medium. © 2010 American Chemical Society and Division of Chemical Education, Inc.

引用

页码：965 / 968

页数：4

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