Adverse childhood experiences and child mental health: an electronic birth cohort study

被引:26
作者
Lowthian, Emily [1 ,2 ]
Anthony, Rebecca [2 ,3 ]
Evans, Annette [4 ]
Daniel, Rhian [4 ]
Long, Sara [2 ]
Bandyopadhyay, Amrita [5 ]
John, Ann [1 ,3 ]
Bellis, Mark A. [6 ]
Paranjothy, Shantini [7 ]
机构
[1] Swansea Univ, Sch Med, Populat Data Sci, Singleton Pk, Swansea SA2 8PP, W Glam, Wales
[2] Cardiff Univ, Sch Social Sci, DECIPHer, 1-3 Museum Pl, Cardiff CF10 3BD, Wales
[3] Cardiff Univ, Wolfson Ctr Young Peoples Mental Hlth, Cardiff, Wales
[4] Univ Hosp Wales, Div Populat Med, Heath Pk, Cardiff CF14 4YS, Wales
[5] Swansea Univ, Sch Med, Natl Ctr Populat Hlth & Wellbeing Res, Singleton Pk, Swansea SA2 8PP, W Glam, Wales
[6] Bangor Univ, Coll Human Sci, Wrexham Technol Pk, Bangor LL13 7YP, Gwynedd, Wales
[7] Univ Aberdeen, Aberdeen Hlth Data Sci Ctr, Inst Appl Hlth Sci, Polwarth Bldg,Foresterhill, Aberdeen AB25 2ZD, Scotland
基金
英国医学研究理事会; 英国惠康基金; 英国经济与社会研究理事会; 英国工程与自然科学研究理事会;
关键词
Adverse childhood experiences; Mental health; Cohort; Wales; Survival analysis; Administrative data; MALTREATMENT; ABUSE; ADOLESCENTS; SYMPTOMS; ENVIRONMENT; DYSFUNCTION; FRAMEWORK; PATHWAYS; BEHAVIOR; OUTCOMES;
D O I
10.1186/s12916-021-02045-x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background Adverse childhood experiences (ACEs) are negatively associated with a range of child health outcomes. In this study, we explored associations between five individual ACEs and child mental health diagnoses or symptoms. ACEs included living with someone who had an alcohol-related problem, common mental health disorder or serious mental illness, or experienced victimisation or death of a household member. Methods We analysed data from a population-level electronic cohort of children in Wales, UK, (N = 191,035) between the years of 1998 and 2012. We used Cox regression with discrete time-varying exposure variables to model time to child mental health diagnosis during the first 15 years of life. Child mental health diagnoses include five categories: (i) externalising symptoms (anti-social behaviour), (ii) internalising symptoms (stress, anxiety, depression), (iii) developmental delay (e.g. learning disability), (iv) other (e.g. eating disorder, personality disorders), and (v) any mental health diagnosis, which was created by combining externalising symptoms, internalising symptoms and other. Our analyses were adjusted for social deprivation and perinatal risk factors. Results There were strong univariable associations between the five individual ACEs, sociodemographic and perinatal factors (e.g. gestational weight at birth) and an increased risk of child mental health diagnoses. After adjusting for sociodemographic and perinatal aspects, there was a remaining conditional increased risk of any child mental health diagnosis, associated with victimisation (conditional hazard ratio (cHR) 1.90, CI 95% 1.34-2.69), and living with an adult with a common mental health diagnosis (cHR 1.63, CI 95% 1.52-1.75). Coefficients of product terms between ACEs and deprivation were not statistically significant. Conclusion The increased risk of child mental health diagnosis associated with victimisation, or exposure to common mental health diagnoses, and alcohol problems in the household supports the need for policy measures and intervention strategies for children and their families.
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页数:13
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