Palladium(II)-Catalyzed N-Carbonylative Cross-Coupling Reaction of Sulfoximines with Aryl, Heteroaryl, and Alkenyl Halides Using Tungsten Hexacarbonyl as Carbon Monoxide Source

Palladium(II)-catalyzed N-acylation was demonstrated through the reaction of N-H sulfoximines with a variety of aryl, heteroaryl, and aryl halides using W(CO)(6) as a source of carbon monoxide, affording N-acylated sulfoximines in good to excellent yields. Moreover, alkenyl bromides underwent palladium(II)-catalyzed N-acylation reactions with N-H sulfoximines, leading to the formation of N-cinnamoyl sulfoximines. This method has the advantages of a broad substrate scope, high functional group tolerance, simple operation, and chemoselectivity between chloride and bromide.