Cu-catalyzed transannulation reaction of pyridotriazoles with terminal alkynes under aerobic conditions: efficient synthesis of indolizines

被引：142
|
作者：
Helan, V. [1 ]
Gulevich, A. V. [1 ]
Gevorgyan, V. [1 ]
机构：
[1] Univ Illinois, Dept Chem, Chicago, IL 60607 USA
来源：
CHEMICAL SCIENCE | 2015年 / 6卷 / 03期
基金：
美国国家科学基金会; 美国国家卫生研究院;
关键词：
N-FUSED HETEROCYCLES; DIAZO-COMPOUNDS; TRISUBSTITUTED FURANS; TOSYLHYDRAZONES; CASCADE; CYCLIZATION; CHEMISTRY; PYRROLES; ALLENES; COUPLING/CYCLIZATION;
D O I：
10.1039/c4sc03358b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A Cu(I)-catalyzed denitrogenative transannulation reaction of pyridotriazoles with terminal alkynes en route to indolizines was developed. Compared to the previously reported Rh-catalyzed transannulation reaction, this Cu-catalyzed method features aerobic conditions and a much broader scope of pyridotriazoles and alkynes.
引用
收藏
页码：1928 / 1931
页数：4
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