Placental Mesenchymal Dysplasia without Fetal Development in a Twin Gestation: A Case Report and Review of the Spectrum of Androgenetic Biparental Mosaicism

被引：11

作者：

Linn, Rebecca L. ^{[1
]}

Minturn, Lucy ^{[1
]}

Yee, Lynn M. ^{[2
]}

Maniar, Kruti ^{[1
]}

Zhang, Yanming ^{[1
]}

Fritsch, Michael K. ^{[1
]}

Kashireddy, Papreddy ^{[1
]}

Kapur, Raj ^{[3
]}

Ernst, Linda M. ^{[1
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Dept Pathol, Chicago, IL 60611 USA

[2] Northwestern Univ, Feinberg Sch Med, Dept Obstet & Gynecol, Chicago, IL 60611 USA

[3] Seattle Childrens Hosp, Dept Pathol, Seattle, WA USA

来源：

PEDIATRIC AND DEVELOPMENTAL PATHOLOGY | 2015年 / 18卷 / 02期

关键词：

androgenetic biparental mosaicism; hydatidiform mole; placental mesenchymal dysplasia; BECKWITH-WIEDEMANN-SYNDROME; COMPLETE HYDATIDIFORM MOLE; INTRAUTERINE GROWTH RESTRICTION; STEM VILLOUS HYPERPLASIA; HAMARTOMA; PREGNANCY; FETUS; IMMUNOHISTOCHEMISTRY; PHENOTYPE; DISORDER;

D O I：

10.2350/14-12-1583-CR.1

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

We report a dichorionic twin gestation with diffuse placental mesenchymal dysplasia (PMD) and androgenetic biparental mosaicism (ABM) involving one twin's placenta with complete absence of fetal development for that twin. To our knowledge, this is the 1st reported case of PMD without fetal development. We discuss the gross, histologic, and genetic hallmarks of PMD and the spectrum of variability depending on degree and distribution of ABM.

引用

页码：146 / 154

页数：9

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