The acidocalcisome

被引：128

作者：

Docampo, R ^{[1
]}

Moreno, SNJ ^{[1
]}

机构：

[1] Univ Illinois, Coll Vet Med, Dept Pathobiol, Mol Parasitol Lab, Urbana, IL 61802 USA

来源：

MOLECULAR AND BIOCHEMICAL PARASITOLOGY | 2001年 / 114卷 / 02期

关键词：

acidocalcisome; calcium; intracellular parasites; Leishmania; malaria; Toxoplasma gondii; Trypanosoma brucei; Trypanosoma cruzi; volutin granule;

D O I：

10.1016/S0166-6851(01)00246-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The acidocalcisome is an electron-dense acidic organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations. Its limiting membrane possesses a number of pumps and exchangers for the uptake and release of these elements. The acidocalcisome does not belong to the endocytic pathway and may represent a branch of the secretory pathway in trypanosomatids and apicomplexan parasites. The acidocalcisome is possibly involved in polyphosphate and cation storage and in adaptation of these microoganisms to environmental stress. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：151 / 159

页数：9

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