Assessment of exocrine pancreatic dysfunction in chronic pancreatitis

被引：11

作者：

Kataoka, K ^{[1
]}

Hosoda, M ^{[1
]}

Yasuda, H ^{[1
]}

Sakagami, J ^{[1
]}

Kato, M ^{[1
]}

Kashima, K ^{[1
]}

机构：

[1] Kyoto Prefectural Univ Med, Dept Internal Med 3, Digest Dis Res Unit, Kamigyo Ku, Kyoto 6020841, Japan

来源：

DIGESTION | 1999年 / 60卷

关键词：

exocrine pancreatic function; secretin test; BT-PABA test; fecal chymotrypsin test; chronic pancreatitis; enzyme replacement therapy;

D O I：

10.1159/000051461

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The clinical diagnosis of chronic pancreatitis is usually based on imaging studies, pancreatic function tests, and the presence of characteristic clinical features. In Japan, diagnostic criteria for chronic pancreatitis were established in 1995, The secretin test (a duodenal intubation test) and the combination of noninvasive tests, N-benzoyl-L-tyrosyl-p-aminobenzoic acid (BT-PABA) and fecal chymotrypsin (FCT), have been recommended for evaluating exocrine pancreatic function in patients with chronic pancreatitis. In the present study, the diagnostic value of these two noninvasive tests was compared to the secretin test. Although noninvasive tests are less sensitive and specific for determining exocrine pancreatic dysfunction than the secretin test, greater reliability for diagnosing chronic pancreatitis can be obtained by performing the BT-PABA and FCT simultaneously, Assessment of exocrine pancreatic function is important not only to diagnose chronic pancreatitis but also to decide a treatment method with pancreatic enzyme preparation.

引用

页码：86 / 92

页数：7

共 26 条

[1] DIAGNOSTIC-VALUE OF THE FECAL CHYMOTRYPSIN TEST IN PANCREATIC INSUFFICIENCY, PARTICULARLY CHRONIC-PANCREATITIS - CORRELATION WITH THE PANCREOZYMIN-SECRETIN TEST, FECAL FAT EXCRETION AND FINAL CLINICAL-DIAGNOSIS [J].