Structural characterisation of an immunomodulating polysaccharide isolated from aqueous extract of Pleurotus florida fruit-bodies

被引：39

作者：

Rout, D ^{[1
]}

Mondal, S ^{[1
]}

Chakraborty, I ^{[1
]}

Pramanik, M ^{[1
]}

Islam, SS ^{[1
]}

机构：

[1] Vidyasagar Univ, Dept Chem & Chem Technol, Midnapore 721102, W Bengal, India

来源：

MEDICINAL CHEMISTRY RESEARCH | 2004年 / 13卷 / 6-7期

关键词：

D O I：

10.1007/s00044-004-0050-6

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The water-soluble glucan was obtained from Pleurotus florida fruit bodies by hot water extraction, ethanol precipitation, DEAE cellulose dialysis and Sephadex G-75 gel filtration. The structural information of the glucan was achieved by chemical (hydrolysis, methylation, periodate oxidation) and spectroscopic (H-1 and C-13) analyses, indicated a repeating unit built up of (1 -> 6)-linked D-glucose. The following structure has been determined for the repeating unit: -> 6)-alpha-D-Glc(p)-(1 -> This fraction exhibited significant macrophage activity through the release of nitric oxide.

引用

页码：509 / 517

页数：9

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