Mechanical circulatory support in the treatment of cardiogenic shock

被引:13
作者
Fernando, Shannon M. [1 ,2 ,3 ]
Price, Susanna [4 ,5 ]
Mathew, Rebecca [6 ]
Slutsky, Arthur S. [7 ,8 ]
Combes, Alain [9 ,10 ]
Brodie, Daniel [11 ,12 ]
机构
[1] Univ Ottawa, Dept Med, Div Crit Care, Ottawa, ON, Canada
[2] Ottawa Hosp Res Inst, Clin Epidemiol Program, Ottawa, ON, Canada
[3] Lakeridge Hlth Corp, Dept Crit Care, Oshawa, ON, Canada
[4] Royal Brompton Hosp, Adult Intens Care Unit, London, England
[5] Imperial Coll, Natl Heart & Lung Inst, London, England
[6] Univ Ottawa, Div Cardiol, Heart Inst, Ottawa, ON, Canada
[7] Univ Toronto, Interdept Div Crit Care Med, Toronto, ON, Canada
[8] St Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Ctr Biomed Res, Toronto, ON, Canada
[9] Sorbonne Univ, Inst Cardiometab & Nutr, Paris, France
[10] Hop Univ Pitie Salpetriere, AP HP, Serv Med Intens Reanimat, Inst Cardiol, Paris, France
[11] Columbia Univ Coll Phys & Surg, Div Pulm Allergy & Crit Care Med, 630 W 168th St, New York, NY 10032 USA
[12] New York Presbyterian Hosp, Ctr Acute Resp Failure, New York, NY USA
关键词
cardiogenic shock; extracorporeal membrane oxygenation; impella; intra-aortic balloon pump; mechanical circulatory support; EXTRACORPOREAL MEMBRANE-OXYGENATION; ACUTE MYOCARDIAL-INFARCTION; INTRAAORTIC BALLOON SUPPORT; VENTRICULAR ASSIST DEVICE; LIFE-SUPPORT; CARDIAC-ARREST; SCIENTIFIC STATEMENT; PREDICTING SURVIVAL; OPEN-LABEL; ECMO;
D O I
10.1097/MCC.0000000000000956
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Purpose of review Cardiogenic shock is a condition that is characterized by end-organ hypoperfusion secondary to reduced cardiac output, and is associated with substantial mortality. The mainstay of therapy for cardiogenic shock is reversal of the underlying cause, and concomitant supportive care with vasoactive medications (vasopressors and inotropes). Patients who continue to deteriorate despite these measures may require mechanical circulatory support (MCS). Here, we review the devices available for MCS, and their associated benefits and risks. Recent findings Despite growing use worldwide, there is little randomized evidence supporting the routine use of any specific device for MCS in cardiogenic shock. A large randomized trial of the intra-aortic balloon pump did not demonstrate short- or long-term improvement in mortality. The TandemHeart and Impella devices which assist in left ventricular unloading have only been evaluated in small randomized trials, which showed an increase in adverse events without improvement in mortality. Finally, venoarterial extracorporeal membrane oxygenation (provides both circulatory and respiratory support) and is currently being evaluated in large randomized clinical trials. Various devices for MCS in cardiogenic shock are available, but routine use is not supported by high-quality randomized evidence. Given the resources required for initiation of MCS, use of these treatments should be limited to centers experienced in advanced cardiac care, and future research should focus on what role (if any) these devices have in clinical practice.
引用
收藏
页码:434 / 441
页数:8
相关论文
共 73 条
[1]   Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications [J].
Abrams, Darryl ;
MacLaren, Graeme ;
Lorusso, Roberto ;
Price, Susanna ;
Yannopoulos, Demetris ;
Vercaemst, Leen ;
Belohlavek, Jan ;
Taccone, Fabio S. ;
Aissaoui, Nadia ;
Shekar, Kiran ;
Garan, A. Reshad ;
Uriel, Nir ;
Tonna, Joseph E. ;
Jung, Jae Seung ;
Takeda, Koji ;
Chen, Yih-Sharng ;
Slutsky, Arthur S. ;
Combes, Alain ;
Brodie, Daniel .
INTENSIVE CARE MEDICINE, 2022, 48 (01) :1-15
[2]   Position paper for the organization of ECMO programs for cardiac failure in adults [J].
Abrams, Darryl ;
Garan, A. Reshad ;
Abdelbary, Akram ;
Bacchetta, Matthew ;
Bartlett, Robert H. ;
Beck, James ;
Belohlavek, Jan ;
Chen, Yih-Sharng ;
Fan, Eddy ;
Ferguson, Niall D. ;
Fowles, Jo-anne ;
Fraser, John ;
Gong, Michelle ;
Hassan, Ibrahim F. ;
Hodgson, Carol ;
Hou, Xiaotong ;
Hryniewicz, Katarzyna ;
Ichiba, Shingo ;
Jakobleff, William A. ;
Lorusso, Roberto ;
MacLaren, Graeme ;
McGuinness, Shay ;
Mueller, Thomas ;
Park, Pauline K. ;
Peek, Giles ;
Pellegrino, Vin ;
Price, Susanna ;
Rosenzweig, Erika B. ;
Sakamoto, Tetsuya ;
Salazar, Leonardo ;
Schmidt, Matthieu ;
Slutsky, Arthur S. ;
Spaulding, Christian ;
Takayama, Hiroo ;
Takeda, Koji ;
Vuylsteke, Alain ;
Combes, Alain ;
Brodie, Daniel .
INTENSIVE CARE MEDICINE, 2018, 44 (06) :717-729
[3]   Ethical Dilemmas Encountered With the Use of Extracorporeal Membrane Oxygenation in Adults [J].
Abrams, Darryl C. ;
Prager, Kenneth ;
Blinderman, Craig D. ;
Burkart, Kristin M. ;
Brodie, Daniel .
CHEST, 2014, 145 (04) :876-882
[4]   Trends in cardiogenic shock complicating acute myocardial infarction [J].
Aissaoui, Nadia ;
Puymirat, Etienne ;
Delmas, Clement ;
Ortuno, Sofia ;
Durand, Eric ;
Bataille, Vincent ;
Drouet, Elodie ;
Bonello, Laurent ;
Bonnefoy-Cudraz, Eric ;
Lesmeles, Gilles ;
Guerot, Emmanuel ;
Schiele, Francois ;
Simon, Tabassome ;
Danchin, Nicolas .
EUROPEAN JOURNAL OF HEART FAILURE, 2020, 22 (04) :664-672
[5]   Predictors of successful extracorporeal membrane oxygenation (ECMO) weaning after assistance for refractory cardiogenic shock [J].
Aissaoui, Nadia ;
Luyt, Charles-Edouard ;
Leprince, Pascal ;
Trouillet, Jean-Louis ;
Leger, Philippe ;
Pavie, Alain ;
Diebold, Benoit ;
Chastre, Jean ;
Combes, Alain .
INTENSIVE CARE MEDICINE, 2011, 37 (11) :1738-1745
[6]   The Evolving Landscape of Impella Use in the United States Among Patients Undergoing Percutaneous Coronary Intervention With Mechanical Circulatory Support [J].
Amin, Amit P. ;
Spertus, John A. ;
Curtis, Jeptha P. ;
Desai, Nihar ;
Masoudi, Frederick A. ;
Bach, Richard G. ;
McNeely, Christian ;
Al-Badarin, Firas ;
House, John A. ;
Kulkarni, Hemant ;
Rao, Sunil, V .
CIRCULATION, 2020, 141 (04) :273-284
[7]   SCAI clinical expert consensus statement on the classification of cardiogenic shock This document was endorsed by the American College of Cardiology (ACC), the American Heart Association (AHA), the Society of Critical Care Medicine (SCCM), and the Society of Thoracic Surgeons (STS) in April 2019 [J].
Baran, David A. ;
Grines, Cindy L. ;
Bailey, Steven ;
Burkhoff, Daniel ;
Hall, Shelley A. ;
Henry, Timothy D. ;
Hollenberg, Steven M. ;
Kapur, Navin K. ;
O'Neill, William ;
Ornato, Joseph P. ;
Stelling, Kelly ;
Thiele, Holger ;
van Diepen, Sean ;
Naidu, Srihari S. .
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 2019, 94 (01) :29-37
[8]   Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international Extracorporeal Life Support Organization Registry [J].
Barbaro, Ryan P. ;
MacLaren, Graeme ;
Boonstra, Philip S. ;
Combes, Alain ;
Agerstrand, Cara ;
Annich, Gail ;
Diaz, Rodrigo ;
Fan, Eddy ;
Hryniewicz, Katarzyna ;
Lorusso, Roberto ;
Paden, Matthew L. ;
Stead, Christine M. ;
Swol, Justyna ;
Iwashyna, Theodore J. ;
Slutsky, Arthur S. ;
Brodie, Daniel .
LANCET, 2021, 398 (10307) :1230-1238
[9]   Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry [J].
Barbaro, Ryan P. ;
MacLaren, Graeme ;
Boonstra, Philip S. ;
Iwashyna, Theodore J. ;
Slutsky, Arthur S. ;
Fan, Eddy ;
Bartlett, Robert H. ;
Tonna, Joseph E. ;
Hyslop, Robert ;
Fanning, Jeffrey J. ;
Rycus, Peter T. ;
Hyer, Steve J. ;
Anders, Marc M. ;
Agerstrand, Cara L. ;
Hryniewicz, Katarzyna ;
Diaz, Rodrigo ;
Lorusso, Roberto ;
Combes, Alain ;
Brodie, Daniel .
LANCET, 2020, 396 (10257) :1071-1078
[10]   Improved Survival With Extracorporeal Cardiopulmonary Resuscitation Despite Progressive Metabolic Derangement Associated With Prolonged Resuscitation [J].
Bartos, Jason A. ;
Grunau, Brian ;
Carlson, Claire ;
Duval, Sue ;
Ripeckyj, Adrian ;
Kalra, Rajat ;
Raveendran, Ganesh ;
John, Ranjit ;
Conterato, Marc ;
Frascone, Ralph J. ;
Trembley, Alexander ;
Aufderheide, Tom P. ;
Yannopoulos, Demetris .
CIRCULATION, 2020, 141 (11) :877-886