PHYLOCHIPANALYSER - a program for analysing hierarchical probe sets

被引：13

作者：

Metfies, Katja ^{[1
]}

Borsutzki, Philipp

Gescher, Christine ^{[1
]}

Medlin, Linda K. ^{[1
]}

Frickenhaus, Stephan ^{[1
]}

机构：

[1] Alfred Wegener Inst Polar & Marine Res, D-27570 Bremerhaven, Germany

来源：

MOLECULAR ECOLOGY RESOURCES | 2008年 / 8卷 / 01期

关键词：

analysis; DNA microarrays; hierarchical probes; molecular probes; phylochips; software tool;

D O I：

10.1111/j.1471-8286.2007.01927.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The recent introduction of phylochips that contain molecular probes facilitates environmental microbial identification in a single experiment without previous cultivation. A set of probes recognizing species at different taxonomic levels is denoted as a hierarchical set. Application of hierarchical probe sets on a DNA microarray allows the assessment of biodiversity with different resolutions. It significantly increases the robustness of the results retrieved from phylochip experiments because of the possible consistency checks of hybridization across different taxonomic levels. Here, we present a computer program, PHYLO-CHIPANALYSER, for the hierarchy editing and the evaluation of phylochip data generated from hierarchical probe sets.

引用

页码：99 / 102

页数：4

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