First-in-human study of PF-05212384, a small molecule intravenous dual inhibitor of PI3K and mTOR in patients with advanced cancer: preliminary report on safety and pharmacokinetics

被引:1
|
作者
Shapiro, G. I. [1 ]
Molina, J. [2 ]
Bendell, J. [3 ]
Brana, I. [4 ]
Spicer, J. [5 ]
Kwak, E. [6 ]
Pandya, S. [7 ]
Millham, R. [8 ]
Houk, B. [9 ]
Bell-McGuinn, K. [10 ]
机构
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
[2] Mayo Clin, Rochester, MN USA
[3] Sarah Cannon Canc Res Inst, Nashville, TN USA
[4] Val dHebron Hosp, Barcelona, Spain
[5] Guys Hosp, London SE1 9RT, England
[6] Massachusetts Gen Hosp, Boston, MA 02114 USA
[7] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA
[8] Pfizer Oncol, NIA, New London, CT USA
[9] Pfizer Oncol, NIA, La Jolla, CA USA
[10] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA
来源
EJC SUPPLEMENTS | 2010年 / 8卷 / 07期
关键词
D O I
10.1016/S1359-6349(10)72094-2
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:123 / 123
页数:1
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