Synthesis of Some 2-Thioxo-imidazolidin-4-one Derivatives and its Antimicrobial Activity

被引：3

作者：

Nasser, A. Jamal Abdul ^{[1
]}

Idhayadhulla, A. ^{[1
]}

Kumar, R. Surendra ^{[1
]}

Selvin, J. ^{[2
]}

机构：

[1] Jamal Mohamed Coll, PG & Res Dept Chem, Tiruchirappalli 620020, Tamil Nadu, India

[2] Bharathidasan Univ, Dept Microbiol, Tiruchirappalli 620024, Tamil Nadu, India

来源：

E-JOURNAL OF CHEMISTRY | 2010年 / 7卷 / 04期

关键词：

2,6-Diphenylpiperidine-4-one; 2-Thioxo-imidazolidin-4-one; Antimicrobial activity; HYDANTOINS;

D O I：

10.1155/2010/292461

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Series of newly prepared 3-{[2,6-bis(4-substituted phenyl)-1-methylpiperidin- 4- ylidene] amino}- 2-thioxo-imidazolidin-4-one derivatives (3a-3f) have been synthesized by the cyclization of compound (2a-2f), ethyl chloro acetate and fused sodium acetate. The chemical structures were confirmed by IR, H-1 NMR and elemental analysis. The synthesized compounds were screened for their antimicrobial activity against four antibacterial and four antifungal organisms.

引用

页码：1320 / 1325

页数：6

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