Leukocytes in Mammary Development and Cancer

被引：148
作者：
Coussens, Lisa M. [2 ,3 ]
Pollard, Jeffrey W. [1 ]
机构：
[1] Albert Einstein Coll Med, Dept Obstet & Gynecol & Womens Hlth, Dept Dev & Mol Biol, Ctr Study Reprod Biol & Womens Hlth, New York, NY 10461 USA
[2] Univ Calif San Francisco, Dept Pathol, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA 94143 USA
来源：
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY | 2011年 / 3卷 / 03期
关键词：
TUMOR-ASSOCIATED MACROPHAGES; STIMULATING FACTOR-I; ENDOTHELIAL GROWTH-FACTOR; GENE-EXPRESSION ANALYSIS; CD4(+) T-CELLS; ANGIOGENIC SWITCH; GLAND DEVELOPMENT; BREAST-CANCER; MOUSE MODEL; MAST-CELLS;
D O I：
10.1101/cshperspect.a003285
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Leukocytes, of both the innate and adaptive lineages, are normal cellular components of all tissues. These important cells not only are critical for regulating normal tissue homeostasis, but also are significant paracrine regulators of all physiologic and pathologic tissue repair processes. This article summarizes recent insights regarding the trophic roles of leukocytes at each stage of mammary gland development and during cancer development, with a focus on Murids and humans.
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页码：1 / 22
页数：22
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