Solvent-controlled Csp2→O silyl migration:: The "one-pot" synthesis of 2,3-disubsituted thiophenes

被引：21

作者：

Devarie-Baez, Nelmi O. ^{[1
]}

Shuhler, Brian J. ^{[1
]}

Wang, Hua ^{[1
]}

Xian, Ming ^{[1
]}

机构：

[1] Washington State Univ, Dept Chem, Pullman, WA 99164 USA

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 22期

关键词：

D O I：

10.1021/ol702149c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An effective "one-pot" synthesis of disubstituted thiophene derivatives employing 3-bromo-2-silyl thiophenes has been developed. A solvent-controlled [1,4] C-sp2 -> O silyl migration was involved as the key step in this process.

引用

页码：4655 / 4658

页数：4

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