Subacute thyroiditis in a patient with psoriatic arthritis switched from secukinumab to adalimumab: a case report and literature review

被引：7

作者：

Nakagawa, Jun ^{[1
]}

Fujikawa, Keita ^{[2
]}

Akagi, Midori ^{[2
]}

Nakaji, Keita ^{[1
]}

Yasui, Junichi ^{[1
]}

Hanatani, Yumi ^{[3
]}

Hara, Toshihide ^{[3
]}

Mizokami, Akinari ^{[1
]}

Kawakami, Atsushi ^{[4
]}

机构：

[1] Isahaya Gen Hosp, Japan Community Healthcare Org, Dept Internal Med, Isahaya, Japan

[2] Isahaya Gen Hosp, Japan Community Healthcare Org, Dept Rheumatol, 24-1 Eishohigashi Machi, Isahaya, Japan

[3] Isahaya Gen Hosp, Japan Community Healthcare Org, Dept Dermatol, Isahaya, Japan

[4] Nagasaki Univ, Grad Sch Biomed Sci, Dept Immunol & Rheumatol, Nagasaki, Japan

来源：

MODERN RHEUMATOLOGY CASE REPORTS | 2021年 / 5卷 / 01期

关键词：

Subacute thyroiditis; psoriatic arthritis; adalimumab; INTERFERON-ALPHA THERAPY;

D O I：

10.1080/24725625.2020.1741116

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 71-year-old Japanese female with psoriatic arthritis (PsA) was admitted for fever and neck pain. Her medication had been switched from secukinumab, an interleukin (IL)-17A inhibitor, to adalimumab, a tumour necrosis factor (TNF)-alpha inhibitor, due to secondary failure for PsA. She was diagnosed with subacute thyroiditis (SAT) on the basis of thyroid hormone levels and thyroid ultrasound findings. Her SAT symptoms improved with prednisolone administration (15 mg/day). Following the administration of ixekizumab, an IL-17A inhibitor, her PsA improved without SAT relapse. SAT mechanism associated with TNF inhibitors remains unknown, but cytokine imbalance may be involved.

引用

页码：36 / 39

页数：4

共 23 条

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