Novel heterocyclic β-nitroenamines-based on a one-pot three-component reaction: a facile synthesis of fully substituted 1H-pyrrolo[1,2-a]-fused-1,3-diazaheterocycles

被引：29

作者：

Alizadeh, Abdolali ^{[1
]}

Rezvanian, Atieh ^{[1
]}

Deng, Yuan ^{[2
]}

机构：

[1] Tarbiat Modares Univ, Dept Chem, Tehran 14115, Iran

[2] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

来源：

TETRAHEDRON | 2010年 / 66卷 / 52期

关键词：

1; n-Diamines; 1,1-Bis(methylthio)-2-nitroethen; Diaroylacetylene; 1H-Pyrrolo[1,2-a]-fused-1,3-diazaheterocycles; Multicomponent reaction; 4-COMPONENT REACTION; MULTICOMPONENT REACTION; ANTIVIRAL ACTIVITY; DRUG DISCOVERY; CYTO-TOXICITY; DERIVATIVES; INHIBITORS; SANGIVAMYCIN; TOYOCAMYCIN; CHEMISTRY;

D O I：

10.1016/j.tet.2010.10.052

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot multicomponent synthesis of a novel class of 2,3-dihydro-1H-pyrrolo[1,2-a]imidazoles, 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrimidines, and 2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a][1,3]diazepines, starting from simple and readily available inputs including diveres diamines, 1,1-bis(methylthio)-2-nitroethen and diaroylacetylene, in excellent yields is described. (C) 2010 Elsevier Ltd. All rights reserved.

引用

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页码：9933 / 9937

页数：5

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