Optimization of water-in-oil nanoemulsions by mixed surfactants

被引：126

作者：

Peng, Li-Ching ^{[1
,2
]}

Liu, Chi-Hsien ^{[1
]}

Kwan, Chang-Chin ^{[2
]}

Huang, Keh-Feng ^{[2
]}

机构：

[1] Cheng Gung Univ, Grad Inst Biochem & Biomed Engn, Tao Yuan, Taiwan

[2] Providence Univ, Dept Appl Chem, Taichung 43309, Taiwan

来源：

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS | 2010年 / 370卷 / 1-3期

关键词：

Water-in-oil nanoemulsion; Phase inversion temperature (PIT) method; Ostwald ripening; W/O NANO-EMULSIONS; ENERGY EMULSIFICATION METHODS; INVERSION TEMPERATURE METHOD; PHASE INVERSION; NONIONIC SURFACTANTS; PIT METHOD; THERMAL-CONDUCTIVITY; CONSTANT-TEMPERATURE; REVERSE MICELLES; STABILITY;

D O I：

10.1016/j.colsurfa.2010.08.060

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The formation of water-in-oil (W/O) nanoemulsions in isohexadecane/mixed nonionic surfactant/water system has been achieved by a low-energy emulsification. Effects of polyoxyethylene 2-lauryl ether (C12E2) and polyoxyethylene 4-lauryl ether (C12E4) on the water in isohexadecane emulsions were systematically studied. Ratios of the two-surfactant mixture, surfactant concentrations, and oil fraction were evaluated by gauging droplet size with the aid of photon correlation spectroscopy. Hydrophilic-lipophilic balance temperature (T-HLB) and phase diagram were used to characterize the nanoemulsion system. The stability of the emulsions prepared was assessed based on the change in droplet size as a function of time. Instability mechanisms including coalescence and Ostwald ripening for the nanoemulsion system are discussed. The addition of a second surfactant could provide more stable nanoemulsions with the minimum size than only one surfactant. Finally, a nanoemulsion composition was optimized and found to be highly stable over a 200-day storage period. The optimum composition for W/O nanoemulsion is isohexadecane/C12E2/C12E4/water 70:6:4:20 wt%. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：136 / 142

页数：7

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